Lgv (Lymphogranuloma Venereum)

Lymphogranuloma Venereum
Dr. Yashika

Causative agent : Chlamydia trachomatis
Incubation period: 3-30 days

Clinical features :
Initial phase:
Painless papule, pustule or ulcer in vulva, urethra,
rectum or cervix.
Involved inguinal nodes feels rubbery.
Acute lumphangitis and lymphadenitis.
Necrosed glands and abscess formation.
Rupture of abscess occurs within 7-15 days.
Sinus and fistula formation.
Intense fibrosis with lymphatic drainage.


Secondary phase : Painful adenopathy.
Classical clinical sign:
Groove sign
A depression between the groups of inflammed nodes.

Complication:
Vulval elephantiasis
Perineal scarring
Rectal stricture
Sinus and fistula formation.

Diagnosis
Culture and isolation
Detection of LGV


Treatment:
Doxycycline 100 mg BID x 21days.
Azithromycin 1 gm PO weekly x 3 weeks
Abscess aspiration

1. Lymphogranuloma Venereum Dr. Yashika

2. Causative agent : Chlamydia trachomatis Incubation period: 3-30 days

3. Clinical features : Initial phase: Painless papule, pustule or ulcer in vulva, urethra, rectum or cervix. Involved inguinal nodes feels rubbery. Acute lumphangitis and lymphadenitis. Necrosed glands and abscess formation. Rupture of abscess occurs within 7-15 days. Sinus and fistula formation. Intense fibrosis with lymphatic drainage.

4. Secondary phase : Painful adenopathy . Classical clinical sign: Groove sign A depression between the groups of inflammed nodes.

5. Complication: Vulval elephantiasis Perineal scarring Rectal stricture Sinus and fistula formation.

6. Diagnosis Culture and isolation Detection of LGV

7. Treatment: Doxycycline 100 mg BID x 21days. Azithromycin 1 gm PO weekly x 3 weeks Abscess aspiration