licorice (Glycyrrhiza glabra Linn ).pptx

about licorice (Glycyrrhiza glabra Linn)

1. licorice ( Glycyrrhiza glabra Linn) By : Rufida Bassam El- hosieny

2. Introduction ‏licorice ( Glycyrrhiza glabra Linn) belongs to the Leguminoseae family and has significant nutritional and medicinal properties.

3. Medicinal Properties Licorice has antibacterial,antioxidant , antimalarial, antispasmodic, anti-inflammatory, and antihyperglycemic properties. It is also used to treat ulcers, and viruses like herpes and chronic hepatitis.

4. Mechanisms of Action ‏ Glycyrrhizin inhibits the growth of RNA and DNA viruses, including HIV and hepatitis viruses. It also exhibits anti-inflammatory properties similar to hydrocortisone .

5. ‏Side Effects One of the common side effects of licorice supplementation is elevated blood pressure due to its effect on the renin-angiotensin-aldosterone system. Other potential effects include hypokalemia and sodium retention, but these usually subside with discontinuation.

6. Antioxidant Activity ‏ Licorice root extracts exhibit significant antioxidant properties. Studies have shown that licorice can reduce oxidative stress by scavenging free radicals and inhibiting lipid peroxidation. The antioxidant effect is dose-dependent, with both aqueous and ethanolic extracts showing strong activity.

7. Antihyperglycemic Activity Licorice has been studied for its potential to manage blood glucose levels in diabetic models. It has been shown to improve plasma glucose, insulin levels, and enzyme activities related to glucose metabolism.

8. Enzyme Inhibitory Activity ‏ Licorice has been found to inhibit various enzymes, such as tyrosinase and aldose reductase. This enzyme inhibition contributes to its potential use in cosmetic products for skin whitening and as an anti-inflammatory agent.

9. Thank you