liver gist tumor- a rare case presentation

liver gist a rare tumor case presentation

1. Primary Liver GIST Dr Mohit Gangwal Dr Rakesh Shivhare 1

2. 35 yr / M Pain abdomen and distension 1 month Examination – Anicetric Stable vitals P/A- Palpable lump in left upper quadran t reaching upto umbilicus 2

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7. S urgery Left lateral segmentectomy Specimen 7.1 kg Biopsy- liver tumor specimen composed of spindle cells, immunohistochemical staining for C-Kit and DOG 1 Positive, GIST positive Diagnosis- Primary GIST of Liver 7

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13. GIST are rare tumors located in GIT Origin- Mesenchymal cells Gene mutations- mast cells/ stem cell growth factor- CD117/ PD GRF Alpha Identified primarily in Stomach 50-60%, small Intestine 30-35 %, colon and rectum- 5%, Oesophagus <1% 13