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1. LESSON PLAN
ON
TOPIC : THALASSEMIA
SUBMITTED BY :
DIVYA NAIR
IDENTIFICATION DATA
Course and year : B.Sc Nursing III Sem
Topic : Thalassemia

2. Name of the teacher : Divya Nair
Venue : Lecture Theatre
Duration of teaching : 40 min
Date :
Time :
No. of students :
Language : English and Hindi
Method of teaching : Lecture cum Discussion
A.V Aids used : PPT and Black Board
Previous knowledge of the group : Group had some knowledge about the topic.
GENERAL OBJECTIVE :
By the end of the discussion, students will gain knowledge about Thalassemia
SPECIFIC OBJECTIVES :
By the end of the discussion, students will be able to :

3. ⮚introduce Thalassemia
⮚define Thalassemia
⮚discuss about the types of thalassemia
⮚enlist causes and risk factors of Thalassemia
⮚list down clinical manifestations of Thalassemia
⮚enumerate diagnostic evaluations of Thalassemia
⮚explain about management of Thalassemia
⮚describe the nursing management of thalassemia
S.NO.TIME SPECIFIC CONTENT TEACHING LEARNING A.V EVALUATIO

4. OBJECTIVE ACTIVITY ACTIVITY AIDS N
1 5Min.introduce
thalassemia
INTRODUCTION
Thalassemia, a hereditary (genetic disorder) group of
hemolytic anemia, is characterized by defective
synthesis in the polypeptide chains of hemoglobin or
decreased production of hemoglobin.
Consequently, Red Blood Cells synthesis is also
impaired.
Lecture cum
Discussion
Students are
actively
participating
PPT
and
blackboard
Introduce the
topic.
2 5 Min.define
thalassemia
DEFINITION
Thalassemia, a hereditary disorder is characterized by
defective synthesis in the polypeptide chains of
hemoglobin
Lecture cum
Discussion
Students are
actively
participating
PPT
and
blackboard
What is
thalassemia?
3 5 min discuss about
the types of
thalassemia
TYPES
Alpha thalassemia : defect in alpha chain of
haemoglobin
Alpha thalassemia occurs when one or more of the
four genes (HBA1 and HBA2 on chromosome 16)
needed for making the alpha globin chain of
hemoglobin are variant or missing. As a result there
will be reduction in the synthesis alpha globin chain
Beta thalassemia : defect in beta chain of
haemoglobin
Beta thalassemia occurs when one or both of the two
genes (HBB on chromosome 11) needed for making
the beta polypeptide globin chain of hemoglobin are
defective. As a result there will be reduction in the
synthesis beta globin chain
•Alpha thalassemia silent carrier. One gene is
missing or damaged, and the other 3 are
normal.
•Alpha thalassemia carrier. Two genes are
Lecture cum
Discussion
Students are
actively
participating
PPT
and
blackboard
What are the
types of
thalassemia?.

5. missing.
•Hemoglobin H disease. Three genes are
missing.
•Alpha thalassemia major. All 4 genes are
missing
3 5Min.enlist causes
and risk factors
thalassemia
CAUSES
•Genetic mutation
•Family history
•Ancestry :
✔Alpha thalassemia : southeast, Indian, Chinese
✔Beta thalassemia : Mediterranean (Greek,
Italian), Asian, African
Lecture cum
Discussion
Students are
actively
participating
PPT
and
blackboard
What are the
causes of
thalassemia?
5 5Min.list down
clinical
manifestations
of thalassemia
CLINICAL MANIFESTATIONS
•Alpha thalassemia silent carriers have no signs
Minor thalassemia :
✔Fatigue
✔Shortness of breath
✔Bone abnormalities: Bones may be brittle and
break easily.
✔Heart palpitations
✔Enlarged liver and spleen
✔Gall stone
Major thalassemia :
Lecture cum
Discussion
Students are
actively
participating
PPT
and
blackboard
What are the
clinical
manifestations
of thalassemia?

6. ✔Pale appearance
✔Poor appetite (Anorexia)
✔Dark urine
✔Slowed growth and delayed puberty
✔Jaundice (a yellowish color of the skin or
whites of the eyes)
✔Enlarged spleen, liver, and heart
✔Bone problems (especially bones in the face)
✔Bleeding tendencies (nose bleeds)
✔Frequent infections
6 5 Minenumerate
diagnostic
evaluation of
thalassemia
DIAGNOSTIC EVALUATIONS
•History collection
•Physical examination
•Blood test : CBC, haemoglobin electrophoresis
•Prenatal testing
Lecture cum
Discussion
Students are
actively
participating
PPT
and
blackboard
What are the
diagnostic
evaluations of
thalassemia?
7 10Minexplain about
the management
of thalassemia
MANAGEMENT
• Blood transfusion
•Iron chelation therapy : Chelation therapy aims
to balance the rate of iron accumulation from
blood transfusion by increasing iron excretion
in urine and or faces with chelators
(deferoxamine and deferasirox)
•Folic acid supplements
•Vaccinations to prevent infections
Lecture cum
Discussion
Students are
actively
participating
PPT
and
blackboard
Explain about
the management
of thalassemia?

7. •Bone marrow stem cell transplant
•Surgery : may be needed if body organs such
as spleen or gall bladder are affected
5 mindescribe the
nursing
management of
thalassemia
NURSING MANAGEMENT
•If patient must have regular blood transfusions
and iron chelation therapy, it is important to
continue with treatment as recommended.
•During and after blood transfusion for
thalassemia major; watch for adverse reactions
- shaking chills, fever, rash, itching and hives.
•If patient have regular blood transfusions,
advise the patient to avoid taking vitamins or
other supplements containing iron.
•Instruct the patient to take a supplement of
folic acid (a B vitamin) every day to help body
make new red blood cells.
•Encourage the patient to eating a balanced diet
that contains plenty of nutritious foods can
help feel better and boost energy.
•Advise the patient to protect himself from
infections with frequent hand washing and by
avoiding sick people.
•Advice patient to get flu shot every year and
the pneumococcal vaccine to prevent
infections.
•Instruct the patient to avoid strenuous athletic
activity because of increased oxygen demand
and the tendency toward pathologic fractures
Lecture cum
Discussion
Students are
actively
participating
PPT
and
blackboard
Explain about
the nursing
management of
thalassemia?

8. SUMMARY :
At the end I summarize my topic which included introduction, definition, causes and risk factors, pathophysiology, classification, clinical
manifestation, diagnostic evaluations and management of thalassemia
CONCLUSION :
Thalassemia, a hereditary (genetic disorder) group of hemolytic anemia, is characterized by defective synthesis in the polypeptide chains of
hemoglobin or decreased production of hemoglobin.
Consequently, Red Blood Cells synthesis is also impaired.
BIBLIOGRAPHY :
- Javed Ansari, Comprehensive medical surgical nursing, Edition 2014 Part A. Punjab: Pee Vee Publication, p-291-294
- https://en.wikipedia.org
- https://www.mayoclinic.org