MANAGEMENT OF PARKINSONISM
Prof.drEman Fayez
Professor of neurological
physical therapy faculty of
physical therapy
Cairo University
COMPONENTS OF EXTRAPYRAMIDAL SYSTEM
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BASAL GANGLIA
The term basal gangliaare masses of grey matter deep
within the cerebral hemispheres.
The term is debatable because these masses are nuclei
rather than ganglia
Anatomically, the basal ganglia include the caudate
nucleus, the putamen, and the globus pallidus.
Together they are called the corpus straitum
Functionally, the basal ganglia and their interconnections
and neurotransmitters form the extrapyramidal system.
DESCENDING EXTRA PYRAMIDAL MOTOR TRACT TO SPINAL INTERNEURON AND
MOTOR NEURON
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&
uncrossed
BRAINSTEM Giving rise to following tracts:
Rubrospinal tract
Vestibulospinal tract
Reticulospinal tract
Tectospinal tract
These tracts terminate on anterior horn interneurons. Occasionally they
terminate directly on anterior horn motor neurons.
EXTRAPYRAMIDAL SYSTEM FUNCTIONS
Regulation and integration of voluntary motor activities through
influencing motor instructions sent to the periphery
Has a role in stabilizing the large and complicated systems that
control movement
REGULATION OF TONE
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Extra pyramidal tracts
•some are excitatory and other are inhibitory to muscle
tone
•overall effect –strong inhibitory effect over Gamma
Motor Neuron in anterior horn cell
What will be the effect of extra pyramidal
lesions ?
Hypertonia-Because strong inhibitory effect
over Gamma motor neuron is lost.
PARKINSON’S DISEASE
Parkinson’s disease (PD) is a progressive
neurodegenerative condition affecting mainly
the basal ganglia
Cell death in the substantia nigra (SN) leading to
decrease in brain dopamine (DA). Acetylcholine
will predominate
PARKINSON’S DISEASE-INCIDENCE
Increases dramatically with age
Mean age of onset = 60 y/o
Most common onset in 50-79 y/o age groups
Onset <30 y/o rare
PARKINSON’S DISEASE-PATHOLOGY
Most common site = substantia nigra SN pigmented neurons
Normal convert endogenous & exogenous Levodopa to Dopamine
striatum via nigrostriatal tract
Abnormal marked deficiency of DA in the striatum
Bradykinesia most closely correlates with degree of
striatal DA deficiency
PARKINSON’S DISEASE-PATHOLOGY
Lewy body = intracellular
inclusion body in the SN
-Pathologic hallmark in Parkinson’s brains
Lewy body
CAUSES OF PARKINSONISM
1-Idiopathic :
Parkinson’s disease (paralysis agitans).
The cause is unknown
There is degeneration of substnacianigrapigmented cells leading to deacreseof
dopamin
OTHER CAUSES OF PARKINSONISM
Vascular (rare)
Trauma (e.g. Mohammed Ali)
Encephalitis
Neoplastic
Environmental toxins
Manganese
Pesticides
PARKINSON’S DISEASE-DIAGNOSIS
History & clinical assessment
No specific lab abnormalities
Minimum requirement of 2/3 major clinical features
Resting tremor
Bradykinesia
Rigidity
SIX CARDINAL FEATURES
REST TREMOR
RIGIDITY
FLEXED POSTURE
BRADYKINESIA –HYPOKINESIA
LOSS OF POSTURAL REFLEXES
FREEZING PHENOMENON
TO DIAGNOSE: TWO OF ABOVE, WITH AT LEAST ONE
BEING REST TREMOR OR BRADYKINESIA
PARKINSON’S KEY FEATURES
Stooped posture
Slow and shuffling gait and Festinating gait.
Pill-rolling tremors static type
Uncontrolled drooling, rare arm swinging with walking
Paucity of facial expression (mask-like faces )and decreased blink
rate .
Micrographia.
Change in voice, dysarthria in form of monotonus speech
Labile and depressed, sleep disturbances
Oily skin, excessive perspiration, orthostatic hypotension
PARKINSON’S DISEASE-MOTOR SYMPTOMALOGY
Have to lose 60% of nigral neurons with 80% depletion of striatal DA
before symptoms of PD develop
Insidious onset
Asymmetric
First symptom = tremor
Usually at rest
Pill-rolling, one hand involved
Decreased with purposeful movement
PARKINSON’S DISEASE-MOTOR SYMPTOMALOGY (CON’T)
Bradykinesia = slowness in initiating movement
Muscular rigidity
Feel on passive movement of joint
Smooth resistance lead pipe or superimposed ratchet-
like jerks cogwheel rigidity
Postural instability (late)
PARKINSON’S DISEASE-TREATMENT GOALS
Adequate symptomatic benefit
Minimize disability
Avoid, delay, or reduce complications/side effects
of treatment
Slow or halt progression
of disease
SOME POINTS MUST TAKEN INTO
CONSIDERATIONS
Maintain mobility and flexibility by ROM
Encourage self-care as much as possible
Monitor sleep patterns to avoid injury
Nutrition-may need soft or thickened foods.
Constipation
Speech therapy may be needed
Psychosocial support—impaired memory cognition
ROLE OF PHYSICAL THERAPIST
Design an exercise program to meet patient
particular needs.
Evaluate and treat problems of mobility and
walking.
Evaluate and treat joint or muscle pain which
interfere with the activities of daily living.
Help with poor balance or frequent falling.
Treat difficulties accomplishing activities of daily
living
Recommend and teach the correct use of adaptive
equipment.
ASSESSMENT OF PD PATIENT
General considerations during assessment
1-to minimize effect of drug induced change in performance
on assessment results it must be performed at the same time of
day
2-assessment is repeated for follow up
3-All activities should be timed
4-considering old age problems as artheritis,decreasedsight
and hearing
ASSESSMENT OF PD PATIENT
1-muscle tone
2-functional activities
3-balance
4-posture
5-tremor
6-dextrety
7-respiratory status
8-Range of motion
9-bradykinesia
10-gait assessment
COMMON PROBLEMS IN PARKINSONISM
Disturbance of normal postural background to movement as balance and
righting reflexes are absent or impaired which resulting in:
1-difficulty in changing position,
2-inability to rotate the body to follow the head
3-Limitation of trunk lateral flexion, and extension
4-Stooped posture
COMMON PROBLEMS IN PARKINSONISM CONT.
5-Respiratory problem lead to poor tolerance to exercise
6-Micrographia -small, cramped handwriting
7-Impaired manual dexterity resulting in difficulty in perform ADL
8-Contracture and deformity secondary to inactivity and muscle
imbalance
9-Weakness due to inactivity
ESSENTIAL PD REHABILITATION COMPONENTS IN EARLY AND MIDDLE STAGE
Breathing exercises and exercises connected with breathing
Stretching exercises
Strength training
Rhythmic initiation technique
PNF pattern to enhance rotation and extension
Aerobic activity
Balance training
Posture correction
Speech and Swallowing Rehab
Role of adaptive and assistive devices
SPEECH AND SWALLOWING DIFFICULTIES IN PARKINSON DISEASE
The same PD symptoms that occur in muscles of the body--tremor, stiffness, and slow
movement-can occur in the muscles used in speaking and swallowing. This can cause
A soft voice
Mumbled or fast speech
Loss of facial expression
Problems communicating
Trouble swallowing
OROFACIAL DYSFUNCTIONS
Masked face -reduced facial expression
Lack of spontaneous blinking of eyes
Poor lip closure and tongue movement result in difficulty in
sowllowing
Dysarthria -lower volume quality of the voice
TREATMENT OF OROFACIALFUNCTION
1-ask pt to take deep breath before speak
2-tapping under jaw to stimulate swalwing
3-gentle shaking of inside cheeks to facilitate lip closure
4-PNF
SWALLOWING
Always sit upright
Chew small amounts of food well and swallow it all before adding more.
Put your fork down between bites to slow yourself down
Make yourself swallow twice after every bite.
Take small sips when drinking. Alternate bites of food and sips.
Take only one sip at a time. Do not drink gulp after gulp.
Use of straws!!
Keep your chin slightly down or at least parallel to the table.
Don’t try to drink out of a can. Use a glass instead.
Don’t talk with food in your mouth
TIPS ABOUT DROOLING
If patient tend to drool,heprobably don’t have more saliva then you used to have;
you are just not swallowing it as automatically as before.
Frequent sips of water or sucking on ice chips during the day can help swallow more
often
Always keep head up, with chin parallel to the floor, and lips closed
Drinking more water will help thinning the phlegm
PROBLEM IN GAIT
Decreased arm swing on the affected side
Problems with walking and balance -may experience short
step, slow, shuffling gait and festinating gait or episodes of
"freezing", being unable to initiate a step forward
GAIT TRAINING
Goals :
Lengthen stride
Increase arm swing
Overcome shuffling and festinating gait
Increase trunk rotation
Encourage heel toe gait
METHODS
Floor marking
Use small obstacles
Emphasis turning movement with small steps and wide
base of support
BALANCE, FALLS, AND POSTURE
Balance problems are one of the main symptoms of PD.
Another name for balance problems is postural instability.
Balance problems increase the risk of
falling, especially when combined with other symptoms
and complications of PD, including:
POSTURE
PD can cause many changes in the body.
One easily recognizable change is posture.
The characteristic changes in posture can include:
A forward head position.
Rounding of the shoulders and upper back.
A forward trunk position with increased bending
of the hips and knees.
SOME TYPICAL POOR POSITIONS
Sitting on the couch watching TV.
Leaning over to work on the computer.
Driving/riding in the car.
Looking downward while reading, or propping your head against the
headboard while reading.
EXAMPLE OF POOR SITTING POSTURE
EXAMPLE OF GOOD SITTING POSTURE
BREATHING EXERCISES
STRETCHES
SEATED NECK AND
CHEST STRETCH
SEATED ROTATION
STRETCH
OVERHEAD STRETCH
STANDING BACK STRETCH
HAMSTRING
STRETCH
LYING SHOULDER
STRETCH
SEATED SIDE STRETCH
STANDING SHOULDER
STRETCH
ROTATION STRETCH
CALF STRETCH
ANKLE CIRCLES
STRENGTHENING EXERCISES
BRIDGING
SHOULDER BLADE SQUEEZE
SHOULDER BLADE SQUEEZES
QUAD STRENGTHENING
QUADRAPED TRUNK
PRONE ON ELBOWS
AEROBIC ACTIVITY
AEROBIC ACTIVITY
BALANCE EXERCISES
PREVENTING FALLS
DO NOT pivot your body over your feet when turning. Instead try:
“U-turn” while walking
“U-turn” -Useful for more open
areas. Move your feet & body
together
in an arc...
WHAT ARE ASSISTIVE\ADAPTIVE AIDS?
Adaptive aids are items that can help you stay as independent as
possible for as long as possible.
These devices can make your daily life easier and safer, and improve
your quality of life.
ASSISTIVE AIDS
A urinal (available for both men and women), bedpan, or bedside
commode can help reduce bathroom trips at night
BATHING AND TOILETING AIDS
TRIPODS
Avoid tripod or
quad canes
No
ONE POINT CANE
A straight cane with a rubber
tip is better.
Yes
CONTINU…
HELPFUL BEDROOM AIDS
Helping handle/bed rail
EATING AIDS
TREMOR TREATMENT FIT LIKE A GLOVE
It is a system of sensors and motors that track voluntary
movements and separate them from the involuntary tremors.
The gloves can then suppress the tremor without stopping the
intended movement.