PREGNANCY
INDUCED
HYPERTENSION
Hypertension develops
as a direct result of
gravid state
GESTATIONAL
HYPERTENSION
A sustained raise of blood
pressure to 140/90mmHg or
more in two different
occasions 4 or more hours
apart beyond 20
th
week of
pregnancy or during first 24
hours of delivery in a
previously normotensive
woman
PRE-ECLAMPSIA
development of
hypertension-141/90
with proteinuria
after 20
th
week of
pregnancy
in previously
normotensive non
proteinuric patient
Methyldopa
250mg oral
250-500mg infusion
Watch for postural hypotension
Do investigation to identify the
hemolytic anemia
Avoid working with sharp
instruments and driving as the drug
will induce sleep
Labetalol
Orally-100mg t.i.d
1-2mg/min IV infusion.
Do the liver function test
periodically.
Hydralazine
100mg/4
th
hourly-orally
Watch for maternal
hypotension, tachycardia,
arrhythmia, palpitation.
Watch for sodium
retention.
Nifidipine
5-10mg-orally-t.i.d.
Resume to small activities.
Watch for hypotension.
Help the patient to get up from
the bed.
Use cautiously if there is any
possibility of using the MgSO4
Anticonvulsan
t therapy
Pritchard regime for the
antenatal management of
severe PIH
Zuspan regime for
antenatal management of
severe PIH
Magnesium sulfate
Vasodilation there by
reducing cerebral
ischemia
Magnesium sulfate is
now recommended drug
of choice for routine
anticonvulsant
management of
eclampsia.
Stop magnesium
sulfate if
Respiratory rate <
16/min
Urine output < 25 ml/h
Knee jerks are
sluggish / absent
If magnesium
toxicity is
suspected
Suggested by the
absence of reflexes
1 g IV of calcium
gluconate is given
Nurse`s
Responsibility
Hourly monitoring of deep
tendon reflexes
Hourly monitoring of
respiratory status and
oxygen saturation and it
should remain >14/mt and
>95% respectively.
Ensure availability of
calcium gluconate the
antidote of magnesium
toxicity