MANU.pptx for internship,.................

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1. INTERN SHIP PRESENTATION 2024-25

2. R.P. Industries, Panoli By:- Marwadi Manan EN:- 220102301012 Branch:- Chemical Engg Sem :- 7 th

3. INTRODUCTION OF INDUSTRY ………. RP INDUSTRY R.P. Industries was established in 2006 by Mr. Ishwar R. Mali, the Managing Director of the company, it is located in Gujarat industrial development corporation, at Panoli and Nandesari. R.P. Industries is a constantly-expanding, visionary approach of Mr. Ishwar Mali who have had a strong foothold in pharma & chemical industry from more than two decades. R.P. Group of company India's leading pharma intermediates manufacturer of prazoles and they are committed to manufacture pharma intermediate that will meet the customers and other regulatory requirements.

4. COMPLETE PROCESS OF RAW MATERIAL AT ENTRY TO STORE ………. Entry of raw materials at gate Report of raw materials is fetched by QC Department Entry of raw materials is done at store Dust is removed from raw Material Now, Raw materials is put in quarantine area Then store person come and Collect sample, submit to QC QC take the sample and test it If the raw material is ok then kept under storage room and then it is dispatched

5. RO Plant ………. The raw water supplied from G.I.D.C. Is having about 350 TDS, equivalent to potable water grade. This water is passed through the fast pass reverse osmosis system having filter membranes. This filtered water is used in the manufacturing process having the specification of less than 100 TDS. The inlet and outlet water quality is daily monitored. Sand Filter :- It remove out the maximum sand particle from the liquid. Carbon Filter :- It filter out all the sand from the water and also changes the taste. Cartilage Filter :- It is use to remove the small sand particle left over in liquid. Membrane pipe :- It is used to remove the salt and pollutants. UV Filter :- It is a type of filter used to kill the bacteria contained in the water. Membrane Pipe is clean by citric Acid and Sodium bicarbonate is injected and heated at and circulated around the RO plant After all the stages the processed water is stored in the storage tank.

6. Sand Filter Carbon Filter Cartilage Filter Membrane Pipe UV Filter Storage Tank RO Plant ……….

7. Warehouse . Security Office. Fire And Safety Department. Maintenance Department. Planning Department. Human Resources (HR). Control Room. Production Department. Finished And Goods Store. Effluent treatment plant . DEPARTMENTS……..

8. Physical of lansoprazole ………. Chemical Formula :-C16H14F3N3O2S. Molecular Weight :-369.363 g/mol. Application :- indigestion, heartburn, and Acidity. Colour/Form:- White to brownish-white crystalline powder. Melting Point :- 178-182 °C

9. Manufacturing Process Of lansoprazole ………. The manufacturing process of lansoprazole typically involves several key steps, including the synthesis of the active pharmaceutical ingredient (API) through chemical reactions, purification, and formulation into final dosage forms such as capsules or tablets. The general process can be outlined as follows: Synthesis of Lansoprazole. Purification Process. Formulation Development. Final Packaging.

10. Process Flow Steps of the lansoprazole....... 1 Synthesis of Lansoprazole Starting Materials :- 2-mercaptobenzimidazole3-methyl-4-(2,2,2-trifluoroethoxy)pyridine 2 Purification Process Solvent Extraction :- Use of solvents like dichloromethane for recovery and purification. Crystallization :- Crystallization techniques to isolate pure lansoprazole from the reaction mixture. 3 Formulation Development Palletization :- Agglomeration of fine powders to create stable pellets. Coating :- Application of enteric coatings to protect the drug from gastric acid. Quality Control :- Testing for stability, dissolution, and potency to ensure compliance with pharmaceutical standards. 4 Final Packaging Capsule/Tablets Formation :- Filling of capsules or compressing into tablets. Labeling and Distribution :- Proper labeling and packaging for distribution to pharmacies and healthcare providers.

11. TQM (Total Quality Management) ………. These Are The Following Pillars Of TQM (Total Quality Management):- DWM (Daily Work Management) AM (Autonomous Maintenance) QCC (Quality Control Circle) Kaizen & Poka-yoke 5s & Zlp (Zero Leakage Program)

12. 5S :- 1S – Sort 2S – Set in Order 3S – Shine 4S – Standardize 5S – Sustain 5S is a simple but effective methodology for removing waste From any work environment through better workplace organization, visualization, orderliness, and general cleanliness. ZLP (Zero Leakage Program):- There are 3 types tag in ZLP:- Red Tag :- To identify Leakage Yellow Tag :- Leakage attended Blue Tag :- Leakage temporary attended Leaks are Quantified by Risk Priority Number.(RPN = Severity x Occurrence x Detection).

13. List of Equipment That Are U se in Plant ………. Reactor :- A Reactor is a device which allow to react and mix chemical in the confined space. It is made of material of MOC 316 or MSGL. Types of Reactors: 1. Stainless Steel Reactor 2. Glass Line Reactor 3. Polypropylene Reactor Stainless Steel Reactor:- This reactor is used for mainly to carried out basic media reaction. Glass Lined Reactor: - It is used for mostly acidic chemical reaction.

14. List of Equipment That Are U se in Plant ………. Condenser :- It used to receive high pressure gas and convert it into liquid by compressing. Types of Condenser : Glass Condenser Graphite Condenser Stainless Steel Condenser Primary Condenser :- It is passed through out by cooling water. Secondary Condenser :- It is passed through out by chilied water.

15. List of Equipment That Are U se in Plant ………. Boiler :- Boiler is a device used to make steam from water. Capacity 1.5 TPH at 10 Kg/cm2.Water . These are the important mounting of boiler : level indicator -Used to indicate water and steam level in the boiler. Pressure gauge - Used to measure the pressure inside the boiler. Feed pump -Used to feed water in the boiler when the water lev Man hole -It is a hole in boiler to clean it or for inspection purpose. Safety valve - It is used to remove excess steam from the boiler were the pressure inside the boiler increases.

16. Pipe Colour Coding ………. It is very difficult to identify a pipe out hundred pipe in industry that's why color coding is used to identify the material passing through the pipe. Indian standard covers the color scheme for the identification of the contents of pipelines(IS 2379). There are Three band for colour coding of pipe : 1. Ground colour - cover entire pipe. 2. First colour band - The total length of band is 50mm long. 3. Second colour band - T he total length of band is 6 mm long.

17. Safety Protocol in Industries Always Wear Safety Shoe, Helmet , Goggles Clothing of employee should be formal and it should cover their hand and leg Be aware of your surrounding Follow all the sign board in the plant Inform nearest Employee in case of any danger.

18. Conclusion 1 Comprehensive Insights For a student it's very important for the one to get the practical knowledge which he can correlates with the bookish or theoretical knowledge he learned during his curriculum. I applied for the summer internship at RP Industries. 2 Knowledge Gained I gained all the knowledge about the working of the plant with all the safety at the prior. I also learned how chemical reactions take place in a reactor, Boiler, different labs.