Anoxia complete deprivation of adequate oxygen supply at tissue level. Hypoxia deprivation of adequate oxygen supply at tissue level that results from asphyxia. Asphyxia ( Gk a, not; sphyzein , to throb) Defective oxygenation of the blood ( Exclusion of air from lungs) Literal meaning is without throbbing or pulse, which occurs soon after asphyxia.
What is mechanical asphyxia ??? Broad term denoting an interference Referring to a condition where Any external pressure applied to neck, chest or other areas of the body In such a way that respiration is difficult or impossible
Hanging aka Self-suspension Definition: It is that form of asphyxia Which is caused by suspension of body By a ligature which encircles the neck Constricting force being the weight of the body
Types (1) Depending on degree of suspension (a) Complete hanging - no part of the body touching the ground (b) Partial hanging -partially suspended -some part of the body touches the ground -only head and chest off the ground (whole weight of the body is not necessary)
Complete Hanging Partial Hanging
(2) Depending on the position of the knot (a) Typical hanging knot is just below the occiput on the central part of the back of neck (b) Atypical hanging knot is anywhere other than the occiput
Typical hanging Atypical hanging
(3) According to manner of death 1. Suicidal hanging 2. Homicidal hanging 3. accidental hanging
Fatal period Usually 3 to 5 minutes
Causes of death in hanging Asphyxia trachea 15 kg (most common) Venous congestion jugular veins 2kg Cerebral anaemia carotid arteries 4 to 5kg vertebral artery 20 kg 4. Reflex vagal inhibition 5. Fracture or dislocation of cervical vertebra sudden drop and long fall
Delayed death Aspiration Pneumonia Pulmonary edema Laryngeal edema Infarction of brain Hypoxic encephalopathy Brain absecess
I. Specific finding II. Findings indicating ante-mortem status III. Non- specific findings
I. Specific findings (a) External appearance Most characteristic finding is LIGATURE MARK Type : pressure abrasion around the neck Factors: numerous factors like Material Number of turns Any entangled materials Duration of suspension
Patterned abrasion
Typical appearance in hanging – oblique Above thyroid cartilage Usually discontinuous Inverted V at the knot More prominent on the opposite side of the knot If Patterned identifying material If prolonged suspension parchment like appearance
(b) Internal findings Neck is dissected under blood less field Subcutaneous tissue under the pressure abrasion is pale and dry No prominent haemorrhages/ muscular contusions underneath
Amussat’s sign Transverse carotid intimal tears Long drops
Hyoid fracture – abduction fracture Thyroid cartilage superior horns- can also be fractured Hangman’s fracture Fracture dislocation of C2 from C3 Sudden and long drop As in judicial hanging
Histopathology Suspension within 2 hours of death Perimortem period Similar mark Confirmed by tissue reaction in microscopy enzyme histochemistry
Pseudo-ligature mark Skin folds on the neck May resemble a ligature mark Especially after refrigeration When there is coagulation of subcutaneous fat Conditions: Obese individuals, Infants, Decomposition
Infant neck folds
Simon’s sign Haemorrhage on the ventral surface of the IV disc Beneath the anterior longitudinal ligament In lumbar spine In elongation and overextension
II. Signs of ante-mortem hanging Le-facie sympathique knot presses on cervical sympathetic eyes partly open pupils dilated Sign of ante-mortem hanging
Salivary dribble mark Stimulation of pterygopalatine ganglion submandibular gland gets activated Increased salivary secretion Seen extending from the angle of mouth Opposite to the site of knot Sign of ante-mortem hanging
Inflammatory change around pressure abrasion Microhaemorrhages in the subcutaneous tissue
III. Non- specific findings Face- congested , cyanosed, petechial haemorrhages Tardieu’s spots face and inner aspects of inner eyelids
Glove And stocking hypostasis Seminal discharge++ Urine or faecal discharge ++
Cardinal signs of asphyxia Cyanosis Congestion Edema Petechial haemorrhages Postmortem fluidity of blood
Internal findings: Lungs congested, edematous and tardieu ’ spots Subpleural haemorrhages especially in the interpleural surface All other organs congested, edematous
Cyanosis
Congestion of internal organs Pulmonary congestion
Petechial hemorrhages external and on internal organs
Definition Asphyxia caused by constriction of neck And the constriction force being an external force and not the weight of the body
Types: (1) Ligature strangulation external force is ligature around the neck (2) Manual strangulation / Throttling External force- compression by human hands
(3) Garroting (4) Mugging
(5) Bansdola
Compression by a ligature tied around the neck Constricting force being an external force applied
Postmortem appearance (a) External Ligature mark middle / below thyroid cartilage completely encircles the neck transversely Bruising around Wide area of bruising – bruising
Hanging Ligature strangulation Ligature mark Oblique, discontinuity Above thyroid cartilage, pale looking Horizontal, continuous, below TC, bruising around and inside Subcutaneous tissue Pale Ecchymosis under the mark Hyoid bone Fracture++ -- Thyroid cartilage Fracture less common More common Emphysematous changes in lungs ----- ++++ Carotid arteries Damage +
Compression of the neck caused by human hands
Typical External findings Six penny bruises Oval/ round (1.5 to 2cm wide) contusions Present on the neck due to compression from pulp of fingers Helps in identifying the position of the victim and assailant
Finger nail abrasions Crescentic abrasions Regularly curved comma like abrasions If nails skid parallel linear lines of abrasions
Inward compression fractures Seen in throttling Fingers of the grasping hands squeeze the greater horns towards each other Periosteum on the outside gets fractured Fragment is displaced inwards Called as adduction fracture
Antero-posterior compression fracture Seen in cases of hanging Hyoid bone is forced directly backwards Greater horns hit against the vertebrae and gets diverged Inner periosteum breaks Fragment displaced outwards Called as abduction fracture
Avulsion Fracture Violent lateral or downward movements of thyroid cartilage Or there is traction in thyro -hyoid ligaments Causes are miscellaneous
Palm of one hand placed horizontally over the mouth and nostrils Reinforced by keeping another palm on the top of it at right angles Heel of the upper palm on the front of neck Findings similar
One bamboo stick kept on the back of neck Another one on the front Ends are tied to cause compression Sometimes, one bamboo stick is placed on the front and at the back- pressure applied using a foot
Victim is attacked from behind without warning Either by throwing a ligature and tying it and twisting it with a lever or rod Mode of judicial execution in Spain “ Spanish windlass technique”
Strangulation is caused by holding the neck of the victim in the bend of the elbow Attack usually from behind
It is a general term used to indicate that form of asphyxia where entry of air to the lungs is prevented by any means other than pressure on the neck or drowning .
Modes Smothering Gagging
Overlaying Choking Traumatic asphyxia
(1)Smothering Form of asphyxia caused by closing the external respiratory orifices either by hand Or by other means, or blocking up the cavities of nose and mouth by introduction of a foreign substance
Postmortem appearance Circum -oral pallor Pallor around nose Pressed against pillow– findings can be obsolete Petechiae and congestion are seen in persons who threw a struggle before death
Pillow blood. Saliva and epithelial cells If hands used scratches from nails Lips and gums show bruising and laceration Frenulum tears Face intensely congested Toungue may be bitten
Internal findings: All that of asphyxia ++ Blood stained frothy fluid airpassages Mucus back of mouth Emphysematous changes in lungs
(2) Gagging Asphyxia resulting from forcing a cloth/ other material into the mouth sufficiently deep to block the pharynx Initially through nose airway is patent, once saliva and mucus comes and blocks complete asphyxia
Autopsy findings Congestion of face, petechiae on the face Injuries to nose and mouth may be present Blood may seep into back of throat Gag may be found soaked and hardened Profuse mucus All asphyxial findings
(3) Overlaying Results due to compression of chest so a sto prevent breathing Usually happens with mother and infant on bed Smothering findings like flattening of face and mouth may be present Blood stained froth++++
(4) Choking Form of asphyxia caused by an obstruction within the airpassages Usually between pharynx and bifurcation of trachea. Usually seen as accidental Treated by Heimlich’s maneuver
PM appearance Asphyxial changes profound in cases of prolonged struggle Foreign body found wrapped in blood stained mucoid Mucus in airpassages
Healthy but grossly intoxicated person Who begins a meal, Suddenly turns blue, coughs violently, then collapses Appears to be a heart attack
Mechanism: Decreased gag reflex poorly chewed food bolus is seen obstructing the airpassages PM Appearance: Foreign body seen occluding airpassages Similar to choking
(5)Traumatic Asphyxia Results from respiratory arrest Due to mechanical fixation of the chest By an unyielding substance or object Chest movements are prevented
Causes Crushed in a mob on the floor Crushing by falls of earth or stone Building collpases
Postmortem appearances Intense congestion, petechial and confluent haemorrhages on the head, neck and upper chest above the level of compression Areas of pallor seen at the levels of compression Asphyxial findings++
A method of homicidal smothering and traumatic asphyxia Derived from the story of William Burke
William Burke and William Hare were friends Use to have body supply for medical schools Inorder to keep up with it they use to kill people Invited people were offered alcohol
After throwing their victim to the ground Burke used to sit on them and close their nose and mouth Hare used to drag the body through the room
When the victim is in a certain position Breathing is impaired Eg : upside down hanging torture In addition venous return venous return to the heart may be impaired.
Definition It is a form of asphyxia due to aspiration of fluid into air-passages Caused by submersion in water or other fluid. Complete submersion is not necessary
Typical drowning/primary drowning Water is inhaled into lungs Death occurs within minutes due to cardiac arrest/ fibrillation
Here, water does not enter the lungs Death happens due to sustained laryngeal spasm Due to inrush of water into the nasopharynx or larynx
Near drowning Refers to a submersion victim who is resuscitated and survives for 24 hours Hypoxemia brain damge Electrolyte disturbances Pulmonary edema Cardiac arrhythmias Death may occur due to complications
Hydrocution / submersion inhibition Death results from cardiac arrest due to vagal inhibition As a result of (a)cold water stimulating the nerve endings on the surface (b) water striking epigastrium
(c)cold water entering the ear drums, nasal passages and the pharynx and larynx
Mechanism of Asphyxia Basic deprivation of oxygen caused by obstruction of alveolar spaces is a factor in all types of drowning
Fresh water drowning (1) Blood concn < waterconcn
(2) water denatures the pulmonary surfactant hence even after resuscitation alveolar collapse happens
Sea water / salt water drowning Blood conc < water conc Water is drawn from blood into lungs Severe pulmonary edema is caused Hemoconcentration salts from lungs pass into bloodstream Na+ increases Bradycardia
1. Asphyxia 2. Ventricular fibrillation~ 3 to 5 mins 3. Laryngeal spasm 4. Vagal inhibition- icy cold water 5. Exhaustion 6. Injuries head striking forcibly against some solid object
Postmortem appearance External: Postmortem lividity light pink in colour Froth fine lathery persistent tenacious froth at nostrils
Cutis anserina / goose skin Puckered appearance Spasm of erector pilae muscles due to cold water Hair is upright
Cadaveric spasm Weeds, gravel and other foreign bodies firmly grasped in hands Sign of ante-mortem drowning
Washer womans hands Soddening of the skin occurs due to Water entering the outer layers of skin
Signs of submersion Wrinkling shortly after submersion Bleaching of epidermis 4 to 8 hours Soddening fingertips in 2 to 4 hours Spreads upwards in about 24 hours Skin becomes soddened , thickened and wrinkled in 20 hours
Foreign bodies in air passages antemortem sign (till the least dissectable portion) Or atleast after tracheal bifurcation
Lungs Become volumionous Doughy Crepitant Ballooned out Congestion, edema and haemorrhages+++
Drowning fluid penetrates alveolar walls enters tissues and blood vessels Emphysema aquosum 80 % cases Presumptive evidence of death from drowning
If the victim is unconscious at the time of death, no froth occurs but mere flooding Knows O edema aquosum
Alveolar walls may rupture due to increased pressure during forced expiration Blood vessels rupture hamorrhages Subpleural haemorrhages Paltauf’s Haemorrhages
Fresh water drowning Sea water drowning Ballooned out but light Ballooned out and heavy Pale pink Purplish emphysematous Soft and jelly like Shape retained after removal from body Not retained flattens up Sectioning- crepitus is heard Copious fluid oozes
When a dead body is thrown into water Water can seep into the lung due to hydrostatic pressure Resembles a drowning lung A drowning lung with a froth fluid on sectioning diagnostic of drowning
Unicellular microscopic alagae found in water Complex structure of cell walls Contain silica, chlorophyll and diatomin Corroborative evidence in Ante-mortem drowning
Demonstration Bone marrow is directly digested by nitric and sulfuric acid Water squeezed out from lungs centrifuged and sedimented Observed under microscope
Cadaveric spasm Foreign bodies in air passages Lungs- typical appearance Positive diatom test