Mechanisms underlying Traditional Chinese Medicine.pptx

How is TCM effective?

1. Mechanisms underlying Traditional Chinese Medicine How is TCM effective? Speaker: Chu-Feng Wu M.D. Date: 2024/05/06

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4. Figure 1. Population Included in the CTS-AMI Study

5. Figure 2. Subgroup Analysis for the Primary End Point of 30-Day Major Adverse Cardiac and Cerebrovascular Events

6. Figure 3. Kaplan-Meier Curves for 1-Year Major Adverse Cardiac and Cerebrovascular Events (MACCEs) and Individual Components of MACCEs

7. Figure 4. Post Hoc Landmark Analysis at 30-Day Point for 1-Year Major Adverse Cardiac and Cerebrovascular Events (MACCEs)

8. In Reply In their Letter, Drs Asham and Entezari-Maleki inquire about the TIMI and GRACE risk scores of patients enrolled in our recent study on Tongxinluo. 1 The Table shows the similarity in the distribution of TIMI and GRACE scores at baseline, and the benefit of Tongxinluo in 30-day major adverse cardiac and cerebrovascular events across low-, intermediate-, and high-risk subgroups (all P values for inter- action > .05). In response to the Letter by Dr Zakiev and colleagues about the stability of the effect of Tongxinluo , the ultra-performance liquid chromatography fingerprint for 10 different batches of Tongxinluo capsules was provided in eFigure 1 of Supple- ment 2 of the article. 1 This eFigure showed the stability of the Tongxinluo capsule ingredients.

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10. TCM clinical diagnosis and treatments are based on symptom phenotypes. Sci Adv . 2023;9(43):eadh0215.

11. Network medicine framework reveals generic herb-symptom effectiveness of traditional Chinese medicine, Volume: 9, Issue: 43, DOI: (10.1126/sciadv.adh0215) Sci Adv . 2023;9(43):eadh0215.

12. Network medicine framework reveals generic herb-symptom effectiveness of traditional Chinese medicine, Volume: 9, Issue: 43, DOI: (10.1126/sciadv.adh0215) Sci Adv . 2023;9(43):eadh0215.

13. Network medicine framework reveals generic herb-symptom effectiveness of traditional Chinese medicine, Volume: 9, Issue: 43, DOI: (10.1126/sciadv.adh0215) Sci Adv . 2023;9(43):eadh0215.

14. Network medicine framework reveals generic herb-symptom effectiveness of traditional Chinese medicine, Volume: 9, Issue: 43, DOI: (10.1126/sciadv.adh0215) Sci Adv . 2023;9(43):eadh0215.

15. Overlapping of Functional Gastrointestinal Disorders (FGID) Symptoms exacerbates the severity of the disease accompanied by psychological disorders more hospital/doctor visits (gut-brain interaction disorders)

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17. Am J Chin Med . 2023;51(4):833-857.

18. Am J Chin Med . 2023;51(8):1957-1981.

19. Chronic Respiratory Diseases Common types include asthma, chronic obstructive pulmonary disorder (COPD), pulmonary fibrosis, lung cancer, pneumonia, etc. The pathological mechanism is complex. Compared with the single component, the reasonable combination of the effective components in the prescriptions under the guidance of TCM theory can exhibit a more optimal therapeutic effect. Lancet Respir Med . 2020;8(6):531-533. Biomed Res Int . 2022;2022:3360771. Published 2022 May 9.

20. Am J Chin Med . 2024;52(1):57-88.

21. Am J Chin Med . 2024;52(1):57-88.

22. Am J Chin Med . 2024;52(1):57-88.

23. Am J Chin Med . 2024;52(1):57-88.

24. Am J Chin Med . 2023;51(4):779-806.

25. Am J Chin Med . 2023;51(4):779-806.

26. Take Home Messages Network medicine framework provides a scope to sketch the mechanisms underlying traditional Chinese medicine. Symptom phenotypes may repurpose the ways of treating burdensome diseases. Call for actions on integrative healthcare, emphasizing connections between organs and systems.