Medline

2,337 views 25 slides Mar 24, 2011
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Clinical Databases :
MEDLINE
S.Prasanth Kumar
Dept. of Bioinformatics
Applied Botany Centre (ABC)
Gujarat University, Ahmedabad, INDIA www.facebook.com/Prasanth Sivakumar
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MEDLINE is the U.S. National Library of Medicine's® (NLM)
premier bibliographic database that contains over 18 million
references to journal articles in life sciences with a
concentration on biomedicine.
A distinctive feature of MEDLINE is that the records are indexed
with NLM Medical Subject Headings (MeSH®)
Selection of journals for MEDLINE are based on
Recommendation of the Literature Selection Technical Review
Committee (LSTRC), an NIH-chartered advisory committee of
external experts analogous to the committees that review NIH
grant applications
NLM-initiated reviews which are special priorities for NLM or
other NIH components (Topics covered: history of medicine,
health services research, AIDS, toxicology and environmental
health, molecular biology, and complementary medicine)
MEDLINE

MeSH is the National Library of Medicine's controlled vocabulary
thesaurus. It consists of sets of terms naming descriptors in a
hierarchical structure that permits searching at various levels of
specificity.
MeSH descriptors are arranged in both an alphabetic and a
hierarchical structure.
Most general level : very broad headings. e.g. "Anatomy" or
"Mental Disorders."
More specific headings : more narrow levels of the twelve-level
hierarchy
e.g. "Ankle" and "Conduct Disorder."
There are 26,142 descriptors in 2011 MeSH. There are also over
177,000 entry terms that assist in finding the most appropriate
MeSH Heading,
for example, "Vitamin C" is an entry term to "Ascorbic Acid."
MESH keywords

MESH Applications
The MeSH thesaurus is used by NLM for indexing articles from
5,400 of the world's leading biomedical journals for the
MEDLINE®/PubMED® database .
It is also used for the NLM-produced database that includes
cataloging of books, documents, and audiovisuals acquired by the
Library.
Each bibliographic reference is associated with a set of MeSH
terms that describe the content of the item.
Similarly, search queries use MeSH vocabulary to find items on a
desired topic.
MEDLINE is the primary component of PubMed®, part of the
Entrez series of databases provided by the NLM National
Center for Biotechnology Information (NCBI). MEDLINE may
also be searched via the NLM Gateway

Details of MEDLINE
Time coverage: generally 1946 to the present, with some older
material.
Source: Currently, citations from approximately 5,516 worldwide
journals in 39 languages; 60 languages for older journals. Citations
for MEDLINE are created by the NLM, international partners, and
collaborating organizations.
Updates: Since 2005, between 2,000-4,000 completed references are
added each day Tuesday through Saturday; nearly 700,000 total
added in 2010.
Broad subject coverage: The subject scope of MEDLINE is biomedicine
and health, broadly defined to encompass those areas of the life
sciences, behavioral sciences, chemical sciences, and bioengineering
needed by health professionals and others engaged in basic research
and clinical care, public health, health policy development, or related
educational activities.
MEDLINE also covers life sciences vital to biomedical practitioners,
researchers, and educators, including aspects of biology,
environmental science, marine biology, plant and animal science as
well as biophysics and chemistry. Increased coverage of life sciences
began in 2000.

MEDLINE Searching

MEDLINE Searching

MEDLINE Searching

MEDLINE Searching

MEDLINE Searching

MEDLINE Standard Concept View

MEDLINE Navigating from Tree Top

MEDLINE Navigating from Tree Top

NLM Classification System

NLM Classification System

Understanding NLM Classification System
(Taken Pharmacology as
Example)

Understanding NLM Classification System
(Taken Pharmacology as
Example)

Understanding NLM Classification System
(Taken Pharmacology
(Anti-Inflammatory Agents) as
Example)

NLM Clinicaltrials.gov

NLM Clinicaltrials.gov
AND boolean operator necessary Why?

Searching Strategies

Clinical Trials

Information on Clinical Trials

Information on Clinical Trials
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