Metabolaid, H2020 SME Tool Granted Project

Metabolaid is a functional ingredient comprised of two plant extracts rich in phenolic compounds: Hibiscus sabdariffa and Lippia citriodora. The data collected during the clinical trials and scientific research have shown that the combination of these two plants help consumers lose weight and protect against obesity-related metabolic disorders, thereby contributing to the prevention of cardiovascular diseases.

1. The project has received
funding from the European
Union’s Horizon 2020
research and innovation
programme under grant
agreement No 783838
Natural remedy to help
lose weight and improve
your health

2. Metabolic syndrome comprises a group of risk
factors that affect the normal metabolic
functioning of our body. Its prevalence is
growing at an alarming rate worldwide due to
increased physical inactivity, unhealthy eating
habits, and alcohol/tobacco consumption,
among other reasons. With time, these
conditions can become chronic, and give rise to
cardiovascular disease, diabetes, liver damage
and cancer.
Its name includes “metabolic” since the risk
factors (normally due to unhealthy habits, such
as a sedentary lifestyle, inadequate nutrition
intake, and alcohol/drug consumption) affect
the biochemical pathways of the body, which
with time and become chronic and give rise to
the diseases previously commented.
Metabolic syndrome is not an actual disease, but
a series of unhealthy habits, or in some cases a
hereditary metabolic condition, which, if not
corrected, can eventually become irreversible.

PREVALENCE OF
METABOLIC SYNDROME
WHAT IS METABOLIC
SYNDROME?
Obesity is currently one of the fastest-growing
pandemics in the work, whose prevalence has
doubled since 1980. By this rate, it is estimated
that in certain countries, such as the US and UK,
about half of the adults will be categorized as
obese by 2030.
Excess weight increases the risk to develop
some of the most common and life-threatening
health problems, including cardiovascular
disease, diabetes and certain types of cancers.
In general, these risk factors are a consequence
of poor eating habits (excess sugar intake and
saturated fats) and low physical activity, althou-
gh there are certain genetic conditions or
medications that can make the individual more
prone to have metabolic syndrome.
Approximately 4 million people (2.8 million in
Europe) die every year due to complications
associated with excess weight. In Europe, over
half of adult Europeans are overweight, and 1 in
5 are obese.
In the EU, the sanitary cost for weight-related complica-
tions is 70 billion euros per year, comprising 5% (7% in
Spain) of total sanitary costs. An obese individual is
36% more “expensive” for healthcare costs than a
normal-weight individual, reaching 60% when metabolic
syndrome is also present.
High cholesterol levels
High body mass
index (BMI)
Especially with high abdominal
fat content
Whit low values HDL
and high LDL.
High triglyceride
levels
Hypertension
Hyperglycemia
An individual is diagnosed with metabolic syndrome if they present at least 3 of the following risk factors:
PREVALENCE OF OVERWEIGHT (%), AGE 20 +, BOTH SEXES, 2008
<20 20-39.9 40-59.9 Data not available>60

3. Lemon Verbena
Hibiscus
WHAT IS METABOLAID
®
METABOLAID
®
inhibits fat accumulation
in the adipose tissue and liver.
HOW DOES METABOLAID
®
WORK?
METABOLAID
®
is a branded ingredient based on hibiscus
and lemon verbena extracts, a unique combination that
can help individuals suffering from metabolic syndrome
to improve their health. To this end, METABOLAID
®
presents the following properties:

Also, the sustained consumption of METABOLAID
®
has an
effect in satiety, allowing you to lose weight while not feeling
hungry.
Help lose weight/lower body mass index (BMI)
Decrease “bad” cholesterol (HDL)
Decrease blood triglyceride levels
Decrease blood pressure
Decrease fasting blood glucose levels
· Activation of AMPK (AMP-activated protein) which
acts as a master metabolic switch. The activated form
of AMPK activates mechanisms in the muscles to
transform glucose and fat into energy. In this manner,
the body uses its energy reservoirs over other sources,
making Metabolaid an efficient "fat burner!
· Adipogenesis inhibition by modulating PI3-K/Akt and
ERK pathways.
· Reduce blood viscosity (and therefore reducing blood
pressure) by inactivating cyclooxygenase/prostaglan-
din-endoperoxide synthase.
· Vasodilation by relaxing the vascular endothelium
and inhibiting calcium influx.
· Inhibition of ACE (angiotensin-converting-enzyme inhibitor)
by stimulating angiogenesis.
The various studies that have been performed with
METABOLAID
®
have shown that this ingredient presents
the following properties:

4. OBSERVED RESULTS
Clinical studies have demonstrated that
METABOLAID
®
is an ideal product for
individuals with excess weight, hypercholes-
terolemia/hypertriglyceridemia, and/or hy-
perglycemia, who wish to improve their
health and quality of life.
Furthermore, an increased satiety effect was
observed in the volunteers taking
METABOLAID
®
, which was perceived as
early as 15 days after consuming the
ingredient (analyzed using the VAS question-
naire). In this manner, the volunteers could
more easily follow the diet plan, without
feeling hungry, and with a more positive
attitude. In conclusion, the consumption of
METABOLAID
®
can help lose weight and
normalize cholesterol/triglyceride/ glucose
levels and blood pressure, while also feeling
less hungry. In this manner, METABOLAID
®
helps consumers follow a diet plan and
increase their motivation and adherence to
improve their health and quality of life.
RESULTS VALIDATED IN CLINICAL TRIALS
AFTER 60 DAYS TAKING 500 MG./ DAY
OF METABOLAID
®

WEIGHT LOSS-4 Kg.
-6,5 cmWAISTLINE
-14.6% BLOOD PRESSURE
-8.4 bpmHEART RATE
-3,5 % FASTING BLOOD GLUCOSE
-2.0% BODY FAT
-12.5% TOTAL CHOLESTEROL LEVELS
-19.6% LDL
REDUCE
ABDOMINAL
FA T
ANTIOXIDANT
ANTI-
INFLAMMATORY
EFFECT
LOWER
BLOOD
GLUCOSE
LEVELS
LOWER
CHOLESTEROL
AND
TRIGLYCERIDE
LEVELS
LOWER
BLOOD
PRESSURE
APPETITE
SUPPRESSOR

5. AVAILABLE SOON AT
APPLE STORE AND
GOOGLE PLAY STORE
Detect and track your experience taking this
nutraceutical product with the help of a digital
device.

Once the consumer purchases the product and
downloads the app, the application will help the
consumer monitor their daily habits (eating hours
and frequency, sleep) as well as allow the connec-
tion to other wearable devices to detect health-re-
lated parameters (heart rate, steps taken, body
weight).
For example, METABOLAID
®
is known to have a
significant effect in controlling a consumer´s
appetite. Therefore, the consumer will be able
to detect changes in their diet (such as
avoiding mid-meal or reduce food intake) even
before they would otherwise notice if they did
not use the mobile application.
Also, the app will measure the consumer´s
motivation with the product and their subse-
quent adherence to lifestyle changes. The latter
will be assessed in the form of questions regar-
ding their mood and how they feel at certain
moments of the day.
Therefore, the METABOLAID
®
APP combines
consumer appreciation of the product, changes
in lifestyle habits and digital tracking, giving
the users a personalized, exclusive connection
with the product, and ultimately a more detai-
led control over their overall health.

METABOLAID
®
APP

6. The project has received
funding from the European
Union’s Horizon 2020
research and innovation
programme under grant
agreement No 783838
HEADQUARTERS
Miguel Servet 16, nave 17 · Elche Parque Industrial
Apdo. 580 · 03203 Elche · Alicante · España
T. [phone] · F. [phone]
www.monteloeder.com
[email protected]
[email protected] (Quality dpt.)
[email protected]
MONTELOEDER USA INC
7300 N. Kendall Dr., Suite #470
Miami FL33156 USA
Phone [phone] Ext. 109
www.monteloederUSA.com
WATCH METABOLAID VIDEO
ASIA PACIFIC
Level35-02 (East Wing), QSentral
2A, Jalan Stesen Sentral 2, KL Sentral
Kuala Lumpur 50470, MALAYSIA
313ho,30, Teheran-ro 6-gil,
Gangnam-gu, Seoul, REPUBLIC OF KOREA