MgSO4

SẢN PHỤ KHOA

1. MAGNESIUM SULFATE
DOSAGE INDICATIONS CONTRAINDICATIONS SIDE EFFECTS NURSING
RESPONSIBILITIES
(ADULTS)
 Parenteral
nutrition: 8-24
mEq/day IV
 Mild Magnesium
Deficiency: I g
IM or IV q 6 hr
for 4 doses )32.5
mEq/24 hr
 Severe
Hypomagnesemi
a: Up to 2
mEq/kg IM
within 4 hr o 5 g
(40 mEq)/1000
mL D5W IV
infused over 3
hr.

IM
 Toxemia,
eclampsia,
nephritis: 4-5 g
of a 50 solution
of 4 hr as needed
IV
 1-4 g of 10-20%
solution. Do not
exceed
 For Acute
nephritis
(children)
 to control
hypertension,
 For
Hypomagnesemia
(replacement
therapy)
 For
Preeclampsia/
eclampsia
 short-term
treatment for
constipation.
 Evacuation of the
colon for rectal
and bowel exams
 To correct or
prevent
hypomagnesemia
 Treatment of
Atypical
ventricular
arrhythmias(Tors
ades de pointes)
 Adjunctive
therapy for the
treatment of acute
 It is contraindicated
with allergy to
magnesium
products;
heartblock,
myocardial damage,
abdominal pain,
nausea, vomiting or
other symptoms of
appendicitis; acute
surgical abdomen,
fecal impaction,
intestinal and
biliary duct
obstruction,
Hepatitis.
 Do not give during
2 hr preceding
delivery because of
the risk of
magnesium toxicity
to the neonate
 Use cautiously with
renal imsufficiency
--

 CNS:
Weakness,
Dizziness,
fainting,
sweating (PO)
 CV:
Palpitations
 GI: Excessive
bowel activity,
Perianal
irritations.
 Metabolic:
Hypermagnese
mia and
toxicity in
patients with
renal failure.
 Reserve IV use
in eclampsia for
immediate life
threatening
situations.
 Give IM route
for deep IM
injection of
undiluted (50%)
sol’n for adults;
dilute to a 20%
sol’n for
children.
 Monitor serum
magnesium
levels during
parenteral
therapy.
 Monitor knee-
jerk reflex
 Do not give
magnesium
sulfate to
patient with
abdominal pain,
nausea and
vomiting
 Monitor bowel
function, If

2. 1.5mL/min of a
10% solution. Or
4-5 g of a 250
mL of 5%
dextrose. Do not
exceed
3mL/minute
PO
 Laxative: 10-15
g PO Epsom salt
in glass of water

(PEDIATRICS)

 Parenteral
nutrition(infants)
: 2-10 mEq/day
IV.
 Antiepileptic:
20-40 mg/kg in a
20%
solution,IM,
Repeat as
needed.
 Laxative: 5-10 g
PO Epsom salt in
a glass of water
MI
 Inhibition of
premature labor
 Adjunct
treatment of
exacerbations of
acute asthma.

diarrhea and
and cramping
occur,
discontinue
usage.