MITOCHONDRIA STRUCTURE AND FUNCTIONS

Mitochondria are membrane-bound cell organelles (mitochondrion, singular) that generate most of the chemical energy needed to power the cell's biochemical reactions.This topic covers History,structure and functions of Mitochondria

1. MITOCHONDRIA Mito = Thread Chondrion = Granule “POWER HOUSES OF THE CELL Dr.Ravirala Naresh,Asst. Professor

2. MITOCHONDRIA Albert von Kolliker -1857 “Granules” - cells of muscles. Flemming-1882 Fila Dr.Ravirala Naresh,Asst. Professor

3. MITOCHONDRIA Richard altmann -1890 Bioplast Benda 1897-98 Mitochondria Crystal violet Dr.Ravirala Naresh,Asst. Professor

4. Occurance - RBC,Prokaryotes + Plant & animal Size Variable length of 3-10 µ diameter of 0.2-1.0 µm (average 0.5 µm). Smallest-Yeast Largest- Amphibia Oocyte MITOCHONDRIA Dr.Ravirala Naresh,Asst. Professor

5. Shape Filamentous Granular Rod MITOCHONDRIA Dr.Ravirala Naresh,Asst. Professor

6. Number Functional state More Activity more No Chaos chaos -50,000 Sea urchin egg-1.4-1.5 lakhs Amphibian Oocyte-3,00,000 MITOCHONDRIA Dr.Ravirala Naresh,Asst. Professor

7. two membranes. outer membrane inner membrane 60 AO/6nm Outer membrane transport protein- Porin Resembles Sieve Inner membrane Impermiable Highly folded- Cristae C-face & M- face MITOCHONDRIA Dr.Ravirala Naresh,Asst. Professor

8. 1. Outer compartment/ Peri -Mitochondrial space/Inter membrane space Between outer & innner membrane Continuous with cristae 2. Inner Compartment/Inner chamber/Matrix space Matrix Matrix-Respiratory enzymes,Lipids,Proteins,cDNA , 55s Ribosome MITOCHONDRIA Dr.Ravirala Naresh,Asst. Professor

9. Cristae Inner membrane Finger like Compartments F 0- F 1 Particles MITOCHONDRIA Frogs-Longitudinal Adrenal cortex-transverse WBC-Network like Dr.Ravirala Naresh,Asst. Professor

10. Elementary particles/ Oxysomes /F 1 /F 0- F 1 Particles Base,stalk,head Attaches to M face 100Ao/10 nm space 10 4 -10 5 MITOCHONDRIA 10 nm Head Stalk Base Dr.Ravirala Naresh,Asst. Professor

11. Dr.Ravirala Naresh,Asst. Professor

12. Dr.Ravirala Naresh,Asst. Professor