MULTIPLE MYELOMA (MM) SLIDESHARE PRESENTATION

A cancer of plasma cells.
The plasma cells are a type of white blood cell in the bone marrow. With this condition, a group of plasma cells becomes cancerous and multiplies. The disease can damage the bones, immune system, kidneys and red blood cell count.

1. MULTIPLE MYELOMA
(MM)
BRINCELETM BIJU

2. What is Multiple
Myeloma ?
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Incidence

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Risk factors

5. Multiple myeloma: pathophysiology
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7. Common sites for bone involvement
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8. Clinical manifestations of multiple
myeloma
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10. Mechanism of disease
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11. Stages of MYELOMA
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12. Symptomatic…..
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➢ mpairment
✓Calcium levels increased
✓Renal failure
✓Anemia
✓Bone lesion
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13. Diagnosis
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15. ▪In monoclonal gammopathies&
Myeloma the single cells produce
a homogeneous monoclonal
immunoglobulin (M protein)
characterised by the presence of
a sharp, well defined band with a
single heavy chain and a similar
band with a kappa or lambda
light chain
▪The M protein is identified as a
narrow peak or “spike” in the
gamma , beta or a 2 regions

16. Lab diagnosis
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20. Imaging
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23. Treatment
regimen
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26. Summary
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27. Thank you
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