Multiple Myeloma presentation (medical surgical nursing )

multiple myeloma defintion ,cause ,sign and symptom ,nursing mangment

1. Multiple Myeloma

2. Definition Multiple myeloma is a malignant disorder of plasma cells: accounting for approximately 13% of all hematologic malignancies.

3. Etiology Genetic Environmental factor Exposure to chemical Low level ionization radiation Bone marrow abnormalities

4. Clinical manifestation Sever bone pain Fatigue Weakness related to anemia caused by crowing of marrow by plasma cell Proteinuria and renal insufficiency Electron disturbance including hypercalcemia ,hyperuricemia

5. Diagnostic evaluation Bone marrow aspiration CBC and blood smear Urine and serum analysis Skeletal x ray -

6. MANGMENT NCCN (NATIONAL COMPREHENSVIVE CANCER NETWORK CURRENTLY GUIDEDE 2 TREATMENT Mephalan plus thalidimode or melphalan plus bortezomib Autologous bone marrow transplant supportive care radiation therapy Biophosphonate Allopurional and fluid to treat hyperuricemia Hemodylisis to manage renal failure

7. Nursing diagnosis Acute pain related to destruction of bone and possible pathologic fracture Impaired physical mobility related to pain and possible fracture Fear related to poor prognosis Risk of injury related to complication of disease process