need of vit D in women's health and role of ayurveda in supporting the requirment. pptx

need of vit Din women health has explained in detail

1. Need of Vitamin-D in Women’s Health – Deficiency management through Ayurveda Dr HIMABINDU MD(AYU) Consultant at Siddhayu ayurveda clinic

2. Vitamin D has undoubtedly become the most “trendy” vitamin of the past decade. Is this rightly so? Vitamin D is an essential micronutrient that is essential for human survival. Humans are expected to generate most of their vitamin D requirement from exposure to ultraviolet B rays (UVB) from sunlight. D 3  is synthesized in the skin after exposure to UVB rays, while D 2  originates from plants. Numerous studies suggest that this deficiency affects bones, but can also constitute a significant factor in the development of infections, autoimmune cardiac diseases , neurological and mental conditions , and cancer . More and more reports are appearing concerning substantial importance of vitamin D in male and female reproductive health .

3. Vitamin D: Sources, Synthesis & Metabolism Vitamin D comes in two forms (D 2  and D 3 ) which differ chemically in their side chains.  Vitamin D 3  is produced in the skin from 7-dehydrocholesterol by UV irradiation. The liver and other tissues metabolize vitamin D- to 25OHD, the principal circulating form of vitamin D. 25OHD is then further metabolized to 1,25(OH) 2 D principally in the kidney, by the enzyme CYP27B1. The production of 1,25(OH) 2 D in the kidney is tightly controlled, being stimulated by parathyroid hormone (PTH), and inhibited by calcium, phosphate

4. Sources of vit D

5. The Essential role of Vitamin D 1. Musculoskeletal (bone and muscle health ) • To maintain calcium and phosphate homeostasis 2. Non-skeletal role • Immunomodulation • Cellular proliferation • Cancer prevention • Hypertension and CVD • Insulin production

6. Classification of Vitamin D Deficiency It is categorized into three groups: Vitamin D deficiency Vitamin D insufficiency Vitamin D sufficiency . Vitamin D deficiency categorization depending upon 25-hydroxyvitamin D concentration 25-(OH)D concentration (ng/m1) Vitamin D status Lower than 20 Deficiency Between 20-30 Insufficiency Above 30 Sufficiency Above 150 Risk of toxicity

7. Let’s take look at some of the common symptoms Weakness and Fatigue Dry Skin and Hair Bruising and Bleeding Depression Slow wound healing Skin colour changes Bone fracture Hair loss Muscle pain

8. Causes of Hypovitaminosis D people with dark pigmentation people suffering from milk allergies or are lactose intolerant , restricted to a vegan diet. Preference for cold drinks and juices over milk makes children Vitamin D deficient spend more time working and are involved in less physical activity get inadequate sun exposure Social and religious customs also play a role as women and their infants usually stay indoors, so they are less exposed to the sun and susceptible to be Vitamin D deficiency. Using sunscreen with SPF30 reduces Vitamin D synthesis in the skin by more than 95% Fun fact

9. Vitamin D Toxicity/Hypervitaminosis D if the use of Vitamin D supplements is in excess i.e. above 4000 IU in women and infants leads to – Hypercalcemia Hypercalciuria Hyperphosphatemia Hardening of vessels and tissues and harm to the heart, blood vessels, and kidneys.

10. Special impact on women Health Vit D receptors are found in the ovary(granulosa cells), endometrium and in the fellopian tube epithelium and their presence increases during pregnanacy. Vit D receptors are also seen in the Pitutary gland . Henceforth , the deficiency of this vitamin always impacts the normal functioning of --- hypothalamo-pitutary gonadal axin. Further leading to many reproductive pathologies.

11. Impact on Reproductive system Polycystic ovarian syndrom : Vitamin D is involved in autocrine insulin secretion, thereby playing a role in the pathogenesis of metabolic disturbances . Also insufficient vit D slows down the ovam maturation and enhance the cyst production . GESTATIONAL DIABETES MELLITUS : 1,25(OH)2D induces insulin secretion and decreases the degree of insulin resistance . A decrease in the serum 25(OH)D level by each 5 ng/mL raises the risk of GDM by nearly 30%. ENDOMETRIOSIS : Endometriosis is one of the main endocrine diseases. It affects up to 10% of women of child- bearing age. The inflammatory factor is thought to play the main role in this condition. Low levels of vitamin D have been linked to increased levels of inflammatory markers like C-reactive protein (CRP), interleukin-6 (IL-6), and other inflammatory cytokines

12. UTERINE MYOMAS : Women with vitamin D levels in normal rang- es are less prone to developing myomas. Ani- mal studies have revealed that vitamin D3 re- duces the size of uterine myomas by decreasing MMP expression . PRE-ECLAMPSIA : Vitamin D deficiency is a common finding in pre-eclampsia patients. Its deficiencies have been confirmed in both the preconception period and during pregnancy. It has been found that vitamin D levels that are lower than 20 ng/mL double the risk of pre-eclampsia .

13. In pregnancy : Vitamin D levels are elevated during pregnancy and it is one of the vital nutrients in the development of the feotus. Vitamin D aids in the growth and maturation of the placenta, baby’s implantation, and prenatal programming. It helps in restoring the skeletal functions of the mother and in the production of skeletal functions in newborns. Deficiency can abruptly damage these functions . Deficient mothers are prone to pain in muscles and bones . Vitamin D supplementation to adequate levels can decrease the chances of preterm birth by 40 %. Higher levels of Vit. D can be effective in preventing bacterial vaginosis and thereby preterm labor pain by influencing the antimicrobial response.

14. Osteoporosis and Muscle Weakness: Vitamin D helps to form strong bones by utilizing calcium and phosphorus and maintaining the metabolism of bone. Inadequate levels of Vitamin D can cause bone loss, reduction in bone density, osteopenia, osteoporosis & a greater incidence of fractures. Due to the decline in bone density, the prevalence of fractures increases as the bones start to lose calcium. Rheumatoid Arthritis (RA): Studies reveal that lower Vitamin D levels are related to the risk of developing Rheumatoid arthritis . women having low Vitamin D levels were found to suffer from this autoimmune disease

15. Autoimmune Thyroid Disorders (AITD): AITD includes Grave’s diseases and Hashimoto thyroiditis, both are linked to poor Vitamin D intake levels which are associated with reduced serum 25-OHD concentrations . Cognitive Disorders : Vitamin D maintains the functions of neurotransmitters in the brain such as acetylcholine, serotonin, and dopamine. It also acts as an antioxidant agent, has a defensive action on brain from various free radicals. Hypovitaminosis D can lead to individuals suffering from Parkinson’s disease, Alzheimer’s disease, schizophrenia, depression, anxiety disorders, and dementia

16. What Ayurveda says? Nidana parivarjana Dinacharya /Rithucharya Suryanamaskara Abhhyanga Deepana Snehapana Vamana & virechana Shamana aushadi

17. Nidana parivarjana : Avoid covering the skin with beauty products for most of the hours in the day time . Avoid junk foods and road side food to keep GIT healthy . Try to expose to the sunrays at the time of sunrise and can be exposed to sun till 1hr after the sunrise . Dinacharya : Pratarutthana Shauchavidhi Dantadhavana- Jihva–nirlekhana : Sneha gandusha dharana Abhyanga and Snana

18. Suryanamaskara Exposure to the early morning sunrays Stimulatesthe cells to absorb and activate the provitamin Stimulatesthe harmonal production Relaxes the muscles Increases the circulation Reduces the anxity, depression Improves the respiratory function

19. Shamanaushadi Thiktha rasa pradhana aushadhas =to maintain the health of liver and enhance the hepatic cell activity which in turn converts the pro vit D in to 25OH calciferol . Ex : Panchatiktha gritha , Triphala gritha Other aushadi dravyas : Tila taila , shigru pathra , navaneetha Ashwagandha and Shatavari , Triphala rasayana Arogyavardhini rasa, Tamra bhasma , swarnamakshika bhasma , pravala panchamritha rasa. Shudha Tankana , gokshuradi guggulu , yavakshara , sarjiksara