Neurological complications of alcoholism By Mahmoud shehata
Neurological complications of acute alcohol intoxication and alcoholism
Alcohol and nervous system Acute intoxication Abstinence and withdrawal syndrome Al c ohol a nd dementia , Wernicke´s encefalopathy
Alcohol and nervous system Acute intoxication Changes in behavior , agressivity , incoordination of movement and gait , slurred speach Drowsiness , stupor , c oma , problems with breathing
Alcohol and nervous system Abstinence and withdrawal syndrome Tremulousness Hallucinations Epileptic seizures Confusion Psychomotor and autonomic overactivity , which develops several hours or days after an addictive drinker abstains from alcohol
Alcohol and nervous system Delirium tremens In 10% starts with seizures Profound confusion , gross tremor , hallucinations , autonomic overactivity – fever , tachycardia , dilated pupils 48-96 hours after cessation of drinking
Alcohol and nervous system Al c ohol a nd dementia Chronic abuse of alcohol – c ognitiv e deficit ( loss of neurons , brain atrophy ) Wernicke´s encefalopathy ( hemorhagic ) Korsakov´s syndrom
Alcohol and nervous system Wernicke´s encefalopathy Confusion , eye movement problems , ataxia – dysarthria , ataxia of body and extremities , residual signs Loss of neurons , axons , myelin , small hemorrhagies – corpora mamillaria , around aqueductus , III. and IV. ventricles Th .: Thiamin 100 mg/ day i.m . or i.v . , B-vitamin complex
Alcohol and nervous system Korsakov´s syndrom - a mnestic syndrom with amnesia , confabulations Marchiafava-Bignami syndrom - d emyelinisation of corpus callosum (MRI - hyperintense lesions Confusion , seizures , dementia http://www.scielo.br/scielo.php
Alcohol and nervous system Alcoholic degeneration of cerebellum - cerebellar atrophy Alcoholic polyneuropathy Alcoholic myopathy : Acute necrotisans myopathy Chronic myopathy