New Generation Fungicides

New Generation Fungicides -plant patholgy- defination and classification

1. RVS AGRICULTURAL COLLEGE (Affiliated to Tamil Nadu Agricultural University, Coimbatore-3) THANJAVUR – 613 402 New generation fungicides BY K.UTHAYANITHI 201728088

2. New generation fungicides with novel modes of action It includes systemic as well as contact fungicides with novel mode of action developed from 2001 to till date Technical feature of new generation fungicides are target specific action and safer to non target sites

3. Several truly novel compounds have been launched commercially and have reached an advanced stage of development which effects on respiration, cell membrane components, protein synthesis, signal transduction, and cell mitosis Many of the important plant diseases, which were not controlled satisfactorily by the previous traditional fungicides , can now well managed by the new compounds which are mostly systemic in nature

4. The process of fungicides discovery has undergone a noteworthy change over the period of time. After the era of broad spectrum multisite and site specific systemic fungicides, several novel action fungicides of different chemical classes have been developed in the past two decades.

5. These are more eco- friendly as these are used at much lower doses as compared to the earlier compounds. Most important among these are the strobilurins ( QoIs ), derived from Strobilurus tenacellus , a wild mushroom

6. Other important fungicides Oxazolidinediones Phenoxyquinolines Anilinopyrimidines Valinamides Benzamides Thiocarbamates and Imidazoles Benzamides

7. New generation fungicide Disease crop Strobilurins powdery mildew, downy mildew grapevine and cucurbits Valinamides Oomycere diseases grapevine, potato, tomato and cucurbits Oxazolidinediones potato late blight potato Phenyl- ureas black scurf of potato potato Mandelamides late blight of potato downy mildew Potato grapevine

8. Mode of action Target site of action Active ingredient common name Respiration Complex I: NADH oxidoreductase inhibitors Diflumetorim Complex II: Succinate dehydrogenase Boscalid Complex III: cytochrome bc1 ( ubiquinol oxidase ) at Quinone outside site ( cyt b gene) Azoxystrobin ( Strobilurins )

9. Mode of action Target site of action Active ingredient common name Protein synthesis Signal transduction Methionine biosynthesis Cyprodinil Pyrimethanil Sterol biosynthesis in membranes C-14demethylase in sterol biosynthesis Cyproconazole Difenoconazole Mitosis and cell division Delocalization of spectrin like proteins Fluopicolide

10. THANK YOU