EPIDEMIOLOGY OF NON COMMUNICABLE DISEASES (NCDs ) part 1 Zagazig university By Alaa Nouh Under supervision Of Prof Dr. Mona Aboserea
Learning Objectives : 1 . To understand the definition, risk factors & prevention of the NCDs & to recognize the epidemiology of some common NCDs. 2. To understand the types, risk factors & prevention of accidents . 3. To Recognize the definition of mental health &mental illness , to describe the risk factors affecting mental health, to identify the interaction between physical and mental illness, & to understand different levels of prevention in mental health. 4. To understand the magnitude, new trends in Egypt, risk factors, consequences, and prevention of substance abuse .
Definition of NCD
Common risk factors of (NCDs) Almost all NCDs have unknown cause, but they have some related RFs.
WHO global status Report 2014: identified 5 important RFs for NCDs in the top 10 leading risks to health.
Reasons of the increasing prevalence of NCDs
Transition Items Demographic Epidemiologic Nutrition transition Past situations -↑ Fertility -↑ Mortality ↑ I nfectious diseases ↑ Under nutrition Interventions -Family planning -Prevention & control of infectious disease - Env . sanitation -Immunization -Antibiotics -Insecticides Food production Reducing Famines Shift To -↓ Fertility -↑ Life expectancy -Aging -↓ Infectious diseases -↓ Mortality from infectious diseases ↑ intake of saturated fat & refined carb. + ↓ dietary fibers Present situation NCDs associated with aging. NCDs predominates ↑ Obesity “↑ fat & carb. intake + Sedentary life”
Multi-factorial nature of the risk factors for NCDs
Migration from low risk culture ( e.g. rural areas) to high risk culture (e.g. Urban areas ) follow the new life style → ↑NCDs risk. Migration of population across different cultures
International communication
Environmental changes
Epidemiology of NCDs differs across countries &changing all the time
R apid & successful achievements in the science of risk detection, use of medication & technologies to prevent & control NCDs. However , in the developing countries high cost of NCDs prevention & control programs is challenging. Limited use of scientific progress in management of NCDs
Prevention of ncd
Screening tests
Egypt National Multisectoral Action Plan for Prevention & Control of NCD 2018-2022 (Egypt MAP-NCD) Framework Element Baseline Target 2021 Target 2025 Premature mortality from NCD 25% 15% relative reduction 20% relative reduction Physical inactivity 32.1% 5% relative reduction 10% relative reduction Salt/sodium intake 12.8 g/day 20% relative reduction (10.0 g/ day) 10% relative reduction (9.0 g/ day) Tobacco use 24.4% 10% relative reduction (22.0 %) 20% relative reduction (20 %) Raised blood Pressure 39% 15%relative reduction (33%) 10 %relative reduction (30%) Diabetes & obesity 17.2% DM 31.3% Obesity Halt the rise in DM & obesity Drug therapy to prevent CVD *N/A % 10 % coverage 15% coverage Essential NCDs medicines & basic technologies to treat major NCDs 60% 70% availability 80 % availability *As there is currently no available baseline data, the approach will be piloted in selected PHC settings.
Hypertension
Hypertension “HPN” is one of the major risk factors for CVDs.
Types & RF of hypertension
Screening tests for HPN For screening purpose in the community-based epidemiological cross-sectional studies, these standards could be used. 2 readings should be taken at least 5 minutes apart & average result represents current Bl.Pr . measurement In the medical settings, diagnosis of HPN depends on findings of Bl.Pr . levels for >2 times few weeks apart.
Complications
Prevention
DIABETES MELLITUS
It is a common metabolic disorder of impaired carbohydrate utilization by the body due to insulin deficiency.
RFs
Non-modifiable RF for T2DM M odifiable RF for T2DM
Laboratory diagnosis of DM
Health technology & diabetes management Continuous glucose monitoring (CGM) technology: helps improve glycemic control for adults with T1DM starting at age 18.
Diabetes management in specific groups I ndividualizing pharmacologic therapy for older adults to reduce the risk of hypoglycemia, avoid overtreatment & simplify complex regimens while maintaining personalized blood glucose targets.
New guideline recommends all pregnant women with preexisting T1DM or T2DM should consider daily low-dose aspirin starting at the end of the 1 st trimester → ↓ the risk of pre- eclampsia .
DEFINITION It is an abnormal proliferation of cells in any organ in the body forming mass or tumor. It invades the surrounding tissues and destroys them.