Non Venereal Treponematosis

A presentation on Yaws, Pinta and Endemic Syphilis

1. NON-VENEREAL TREPONEMATOSIS 18.3.19 Dr. Jerriton Brewin , 1 St Year PG, DVL, SVMC

2. YAWS CAUSE T. Pallidum pertenue EPIDEMIOLOGY Rural area Tropical belt High humidity Poor hygiene Early childhood M > F

3. TRANSMISSION Skin-to-skin Flies ( Hippelates pallipes ) INCUBATION 3 – 6 weeks

4. PINTA CAUSE T. Pallidum carateum EPIDEMIOLOGY Rural area Central and South America Poor hygiene Crowded area Half patients < 15 years M = F

5. TRANSMISSION Skin-to-skin Insects INCUBATION 1 – 8 weeks Most benign Has only skin involvement

6. ENDEMIC SYPHILIS (BEJEL) CAUSE T. Pallidum endemicum EPIDEMIOLOGY Nomads in the Arab Peninsula D ry and arid climates Poor hygiene Overcrowding Children < 15 years (80%)

7. TRANSMISSION Skin-to-skin/mucus membrane Shared food Fomites INCUBATION 2 – 4 weeks C/F resemble venereal syphilis Has predominant mucosal involvement

8. DIAGNOSIS High endemicity – clinical diagnosis Eosinophilia ( Pinta ) Darkfield microscopy of serous exudate Serology ( Treponemal & Non- treponemal ) Skin biopsy ( treponema identification with silver stain & immunofluorescence)

9. WHO mass treatment eradication campaigns = 7- to 10-day course of oral penicillin, at a dose of 50 mg/kg per day in four divided doses up to 1,200 mg daily.

10. REFERENCES VK Sharma, STIs. Bhushan Kumar, STIs. Fitzpatrick’s Dermatology Rook’s Textbook of Dermatology