One compartment open I.V. bolus model

GokulDev8 284 views 15 slides Mar 15, 2021
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About This Presentation

Discussing, I V Bolus open compartment model from Pharmacokinetics models. It is as per PCI Syllabus. Extracted from Bramankhar pharmacokinetic book.


Slide Content

COMPARTMENT MODEL The body is represented as a series of compartments arranged either in series or parallel to each other, that communicate reversibly with each other. Site: https://learnpharmeasy.blogspot.com/ y Learn Pharmeasy Central Peripheral Drug Input Elimination

COMPARTMENT MODEL Each compartment is not a real physiologic or anatomic region but a fictitious or virtual one and considered as a tissue or group of tissues that have similar drug distribution characteristics (similar blood flow and affinity). Site: https://learnpharmeasy.blogspot.com/ y Learn Pharmeasy

One-Compartment Open Model Intravenous Bolus Administration When a drug that distributes rapidly in the body is given in the form of a rapid intravenous injection (i.e. i.v. bolus or slug), it takes about one to three minutes for complete circulation and therefore the rate of absorption is neglected in calculations. Site: https://learnpharmeasy.blogspot.com/ y Learn Pharmeasy Blood & Other Body tissues K E

One-Compartment Open Model I.V Bolus – Plasma Data Site: https://learnpharmeasy.blogspot.com/ y Learn Pharmeasy

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Site: https://learnpharmeasy.blogspot.com/ y Learn Pharmeasy One-Compartment Open Model I.V Bolus – Urinary Data

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