Oral aspects of metabolic disorder.pptxb

1. Oral aspects of metabolic disorder Dr. AEBEENA BABU PG

2. VITAMIN C Ascorbic acid- A water soluble vitamin Plays very important role in synthesis of collagen fibers Vitamin c -obtain through diet. Present –Citrus fruits Green vegetables Tomatoes P otatos

3. Functions of Vitamin C Synthesis of collagen Helps in the synthesis of neurotransmitter nor epinephrine Metabolism of cholesterol Highly effective antioxidant Decrease the risk of cardiac diseases, strokes and cancer. Decrease the oxidative stress – reduce the risk of diabetic mellitus

4. Requirements of Vitamin C Infants : range from 35mg Adults : range to 60 mg Pregnant and lactating women – increase their daily intake by 20 mg and 40 mg

5. SCURVY Clinical Features: Oral effects- Gingival and periodontal tissues Interdental and marginal gingiva – bright red with a swollen, smooth and shiny surface. Fully developed scurvy- Gingiva- boggy, ulcerates and bleeds.

6. Acute or chronic scurvy- Gingival ulcer Foul breath Severe chronic scurvy : Hemorrhages and swelling in PDL Loss of bone Loosening of teeth

7. Vitamin B complex

8. Thiamine (B1) Plays an important role in carbohydrate metabolism Its deficiency may lead to “ beri – beri ”- insiduous on onset and chronic in course-sudden death occur Beri – beri –two types Wet Dry

9. Wet beri beri - Dysautonomia Cardiomegaly High output cardiac failure Peripheral edema Peripheral neuritis Dry beri-beri Same symptoms

10. Oral manifestation Edema of tongue Loss of its papillae Glossodynia

11. Requirements Infants : range from 0.3mg Young adults : range to 1.5 mg Pregnant and lactating women-0.4mg -0.5mg

12. NIACIN (Nicotinic acid) Plays an important role in intracellular oxidation process Deficiency causes pellagra

13. Clinical features 4D’s - Dementia Dermatitis Diarrhea Death

14. Disturbed gastrointestinal and neurological functions Nasolabial seborrhea Malar pigmentations Oral manifestations : Generalized stomatitis with burning sensation Swelling Redness ,pain and ulceration etc

15. Tongue – Red Enlarges Depapillated Bald surface Thickly coated with a grayish pigmentation of the surface Severe case- Deep ulcers o n tongue

16. Gingiva – Red Swollen Ulcerated Painful lips and Angular chelitis

17. Riboflavin (B2) Occurs due to malabsorption syndrome Tongue-Reddening Inflammation and depapillation Sore Sometimes ulcerated

18. MAGENTA GLOSSITIS ( P eculiar form of glossitis) M agenta in color Surface in granular or pebbly due to flattening and mushrooming of the papillae Angular chelitis –reddening with fissures ,painful cracks, dry scaling and ulcerations at the corner of the mouth Lip lesions- white patchy lesion

19. FOLIC ACID Given during pregnancy Reduce the risk of neurological defects in child Reduce the risk of development of orofacial clefts

20. CAUSES Malnutrition Pregnancy Malabsorption Drug treatment with phenytoin

21. Oral manifestation Loss of filliform and fungiform papilla –result in smooth shiny appearance Defective keratinization Gingivitis Oral ulcerations Atrophy of tongue papillae with glossitis