What is oxygen therapy?
It is the supplemental oxygen that is given for medical
treatments.
What are the
common
indications for
oxygen therapy?
What are the common indications for oxygen
therapy?
1.Oxygen therapy is readily used to treat hypoxia.
2.Medical conditions like
●Trauma
●Shock
●Myocardial infarction
●Severe asthma
●Chronic obstructive pulmonary diseases
●Cystic fibrosis
WHAT ARE THE TYPES
OF OXYGEN THERAPY?
Types of oxygen therapy:
1.Inhalation of 100% pure oxygen at 1 atmospheric pressure
i.e. 760 mmHg
2.Inhalation of 100% pure oxygen at high barometric pressure
i.e. HYPERBARIC OXYGEN THERAPY
INHALATION OF 100% PURE OXYGEN AT 1 ATM PRESSURE
●Useful only in hypoxic hypoxia
●Administration of oxygen increases the pressure gradient
between the alveoli and the blood and hence the oxygen
entry is facilitated into the blood.
DISADVANTAGES
●Inhalation by normal individuals,
Suppression of
respiratory
centre
Toxic effects on bacteria due to
superoxide anion and H
2
O
2
● Administration for more than 8 hours
causes-
Irritation in respiratory pathways
leading to coughing, nasal congestion,
tachypnoea with bronchoconstriction.
●Administration for 24 hrs causes-
Inhibition of lung macrophages to kill
bacteria.
And decreases the surfactant production
leading to broncho-pneumonia.
Inhalation of 100% pure oxygen at high barometric pressure
●Useful in
1.anemic hypoxia
2.stagnant hypoxia
3.histotoxic hypoxia.
However the underlying caused should
be treated along with supplementation
of oxygen.
●Administration of O2 will increase
the dissolved oxygen in the plasma.
For normal metabolic needs
Oxygen solubility required is 6 ml /100 ml dissolved oxygen
(normal: 0.3 ml/100 ml / mmHg )
Achieved by high barometric pressure oxygen (i.e.3 Atm
pressure)
Disadvantage: oxygen toxicity
●Barometric pressure above 3 atm pressure
●Produces derangement of cerebral activity.
1.Muscular twitching
2.Ringing in ears
3.Dizziness
4.Jerking type of respiration
5.Convulsions and unconsciousness
Due to
•Decrease in brain GABA
and ATP
•Inhibition of tissue enzyme
activity
•Cerebral vasoconstriction