PATHOLOGY OF EYELIDS
AND ADNEXA
OPTOM FASLU
MUHAMMED
Pathology of eyelids and adnexa are similar
to those that occur in skin and appendages
elsewhere in the body
Lesions of eyelids and adnexa are of
following types
1.Cysts
2.Inflammations/infections
3.Metabolic changes & degenerations
4.Tumourous conditions
5.Tumours
Inclusion cysts
Occur in any part of the eyelid following
trauma or infection
Cyst – keratinous lined by stratified
squamous epithelium and the walls do
not contain any appandages
Retention cysts
Result of blockade of ductal opening of
eccrine glands
The cyst may contain clear or
sebeceous material based on the type
of gland involved
Dermoid Cysts
These are encountered in midline
/fusion lines
Frequently seen in infants or
adolescents
Cysts may show intracranial
extension ,containing keratosebaceous
material and are lined by stratified
squamous epithelium
The wall contain appendages such as
sebaceous glands
INFLAMMATIONS /INFECTIONS
Eyelid may be a source of a variety of
specific and non specific infective
disorders
Some of the most frequently
encountered lesions of the eyelid are
presented below
BLEPHARITIS
Type of inflammation affecting the eyelids
may be acute/chronic
Lid margin inflammations are commonly
associated with dandruff and is termed as
seborrhoeic Blepharitis.
Extension of inflammation may be noticed
upto conjunctiva- blepharoconjunctivitis
Staphylococcus is responsible
Hordeolum
Suppurative nonspecific inflammation
of lid
Based on anatomical site of
inflammation -2 forms are recognized
Hordeolum externum
Hordeolum internum
Suppurative
inflammation of
Zeiss and Moll
glands
Hordeolum externum (stye)
Suppurative
inflammation of
Meibomian glands
associated with
blockage of duct
Hordeolum internum
CHALAZION
Chronic non infective granulomatous
inflammation of sebaceous glands of
lids with/without granulomatous reaction
Zeiss gland inflammation- external
chalazion
Meibomian gland-internal chalazion
Other infections/inflammations
Bacterial /myobacterial agents may
produce non granulomatous or
granulomatous reaction accordingly.
Viral infections that affect skin
Molluscum contagiosum
Presence of molluscum bodies
Result of enlargement and distension of
epiderma cells with viral inclusions