Pathology of Urinary Tract Infectionws

UTI

1. Pain nourishes courage . You can't be brave if you've only had wonderful things happen to you. – Mary Tyler Moore

2. BPH2 : Urinary Tract Dis: UTI CPC : Term4 Week3 - BPH 2/6 System : Urinary Tract. Topic : 1: Overview 2: UTI 3: BPH 4: Tumours 5: Obstructions Lithiasis 6: Others 7: GLS

3. UTI: Overview Urethritis , Cystitis, Prostatitis, Pyelonephritis 90% by Escherichia coli * , Recurrence (40%), Uropathogenic strains (UPEC). P fimbriae or pili – bind to urothelium . Colonize colon spread to urinary tract. Staph. Saprophyticus , Proteus, Klebs ., Entero ., Ureaplasma .. - Rare Clinical : Females* , Anatomy*, sexual, UT abnormality / Obstructions. Dysuria , Low grade fever, frequency, urgency, Flank pain, high fever, – pyelonephritis. Complications : E coli septicemia* endotoxins  DIC*, Prostatitis, Prostatic abscess.

4. A friend is someone with whom you dare to be yourself . – Frank Crane

5. UTI: Diagnosis: E coli Blood : Leukocytosis – neutrophilia Midstream clean catch Urine specimen* Dipstick : Leukocyte esterase & nitritie + ve . Urine : pyuria, neutrophils, bacteria, Microscopy gram stain: Gram negative Bacilli, Lactose fermenting . Also Entero .. & Klebsiella ferment lactose. Further tests to confirm : E coli  urease – ve (unlike Klebsiella & Proteus + ve ) MacConkey agar * selective, indicator media. 24h, 37°C, Aerobic, Pink colony ( lactose ferment  acid  pH indicator ), Beta-hemolytic on blood agar.

6. A friend is someone with whom you dare to be yourself . – Frank Crane