Peptic ulcer disease

Peptic ulcer disease presentation for ordinary people

1. Peptic Ulcer Disease Dr. Sanzida Islam (9201) Dr. Kazi A. K. M. Rasel (9202) Dr. Md. Farid Ahmed (9203) Dr. Afroza Sultana (9204) Dr. Abu Toha Md. Shakil (9205)

2. Sites of Peptic Ulcer Stomach Duodenum Lower end of esophagus Jejunum

3. Causes of Peptic Ulcer H. Pylori NSAIDs Heredity Smoking Stress, spicy food steroid, alcohol

4. Pathology Gastric ulcer is single. Usually in antrum or junction between antrum and body. Duodenum ulcer on first part, anterior wall.

5. Clinical Features Epigastric pain Heartburn, loss of appetite and vomiting

6. Difference between gastric and duodenal ulcer Periodicity Pain Vomiting Hemorrhage Appetite Diet Weight

7. Investigations Endoscopy of upper GIT

8. Management: G eneral Measures Avoid smoking Avoid pain killers Regular meal Avoid spicy foods

9. Management H. Pylori eradication T riple Therapy Pain relieve Antacid

10. Management Healing ulcer and prevent relapse proton pump inhibitors H2 blocker Misoprostol Bismuth Sucralfate Surgical Option

11. Differential Diagnosis Acute cholecystitis Acute pancreatitis Acute MI

12. Complications Acute Perforation Hematemesis / melaena Intermediate Residual abscess Chronic Stenosis – pyloric stenosis, hour glass contracture, tea pot deformity Penetration into pancreas Gastric cancer

13. Prevention Diet Avoid Smoking Alcohol Pain Killers Sanitation and food hygiene Reduce stress

14. Conclusion