PERSONALISED MEDICINE IN BIOTECHNOLOGY.pptx

PERSONALISED MEDICINE IN BIOTECHNOLOGY.pptx

1. SAGANA.P II YEAR DEPARTMENT OF BIOTECHNOLOGY sree sastha institute of engineering and technology PERSONALISED MEDICINE

2. CONTENT Introduction Benefits of Personalised medicine Process of personalisation Customized drug delivery design Conclusion References 2

3. INTRODUCTION Personalised medicine is also termed as “Individualized Medicine” Its an ability to offer the Right Drug to the Right patient for Right Disease at Right time with the Right Dose. It enables pharmaceutical company to develop more effective medicine with less side effects. 3

4. BENEFITS OF PERSONALISED MEDICINE Better drug delivery to patient instead of trial and error. Customized pharmaceutical may eliminate the life threatening adverse reactions. Reduced cost of clinical trials by quickly identifying their efficiency of drug. 4

5. Following study involved in the development of personalized medicine: The Human Genome Chromosome The Genetic Code Gene Expression DNA Sequence and Structure 5

6. Understanding Human Genome Simpler methods Identify genetic Information Genetic information specific to individual Preselect effective drug PERSONALISED MEDICINE No Toxicity No Trial and Error 6

7. PROCESS OF PERSONALIZATION The process of personalization starts at the Developmental stage of medicine and based on Pharmacogenomics and Pharmacogenetic . Pharmacogenomics is the study of variation on DNA and RNA characteristics related to drug response. Pharmacogenetic is the study of linkage between individual genotype and individual ability to metabolize a foreign compound. 7

8. CUSTOMIZED DRUG DELIVERY SYSTEM 3D Printing Tele pharmacy Bio Electronic Medicine 8

9. BENEFITS OF 3D PRINTING 3D-Printing: The process of making Three Dimensional Solid object from a Digital file by layer fabrication. Advantages of 3D Printing: High production rate due to Fast Operation System Reduction of material wastage – can save cost of production Ability to achieve accuracy especially for potent drug. 9

10. 3D PRINTING 10 Figure.1. 3D Printing Image Credit: biospectrumasia.com

11. BENEFITS OF 3D PRINTING 11 INCREASED SOLUBILITY REPEATABLE ACCURACY NON-CONTACT PROCESSING MICRO-DOSING WITHOUT OXIDATION DOSAGE- SPECIFIC PARAMETERS UNIQUE DOSAGE FORMS ON-DEMAND FASTER TRIALS BENEFITS OF 3D PRINTING

12. TELE-PHARMACY Telepharmacy is the delivery of pharmaceutical care via telecommunication to the patient in location where they may not have direct contact with a pharmacist. Telepharmacy service includes: Drug monitoring therapy Patient counselling Authorize for P rescription Drug 12

13. BIO ELECTRONIC MEDICINE Bioelectronic Medicine is the application of electronic devices to living organisms for clinical testing diagnosis and therapy 13 Figure.2. Bio Electronic Medicine Image Credit: https://cenbrain.westlake.edu.cn/

14. BIO ELECTRONIC MEDICINE Bio Electronic Medicine includes: Pathogen detection devices- Developing point-of-care devices for the detection of pathogenic bacteria is essential to prevent and treat infections Therapeutic drug monitoring- wearable and implantable biochips - adjust drug dosing in response to patient health conditions enables the management of diseases Lab-on-chip and microfluidics - M icrofluidic -based miniaturized microchips for testing of neurotransmitters 14

15. CONCLUSION Revolutionizing healthcare by tailoring treatments to individual genetic makeup, lifestyle factors, and environmental influences. R epresents a paradigm shift in healthcare delivery, promising improved patient outcomes and a more sustainable healthcare system . Challenges include data privacy concerns, regulatory complexities, and disparities in access to advanced diagnostics and therapies . 15

16. REFERENCES Textbook of personalized medicine second edition- Kewal K Jain MD, FRACS, FFPM Pharmacogenetics - By Allen D Rose’s (2001) Oxford University Press Ursan ID, Chiu L, Pierce A (2013) Three Dimensional Drug Printing: a structural review, J Am Pharm Assoc 53: 136-144 Rugnetta M, Kramer W, Science progress [Homepage on the internet] Sept. 14 [Cited 2010 Dec 27] Personalised Medicine [Homepage on the internet], Copyright; n.d . [Cited 2010 Dec 27] 16

17. THANK YOU 17