PERTUSSIS (WHOOPING
COUGH)
PRESENTED BY
O. MALIYAMA
SPECIFIC OBJECTIVES
•Define pertussis
•Explain the epidemiology of pertussis
•Explain diagnosis of pertussis
•Outline clinical manifestations of pertussis
•Explain management of pertussis
•Explain prevention of pertussis
•Outline complications
DEFINITION
•Pertussis is a highly contagious infection which
results in fits when coughing that usually end
in a prolonged high pitched, deeply in drawn
breath (the whoop).
Causative organism
•It is caused by Bacterium- Bordetella Pertussis
EPIDEMIOLOGY
Incubation period
•21 days
Mode of spread
•Through droplets of an infected person produced
by coughing and sneezing
Communicability
•Mostly transmitted from 7 days after the person
has been exposed to the germs until 3 weeks
after the start of coughing
EPIDEMIOLOGY CT...
Predisposing factors
•Lack of immunisation
•Overcrowding
•Poor nutrition
PATHOPHYSIOLOGY
•The bacteria damage the cells of the
respiratory tract
•The damage produces a clear, very sticky
mucus which blocks the lumen of the
bronchiole
•Children try to get rid of the mucus by
coughing
PATHOPHYSIOLOGY CT...
•The cough may last for many weeks or even
months
•The persistent cough and vomiting and
accompanying sticky mucus may prevent the
child from sucking well
DIAGNOSIS
•A cough illness lasting at least two weeks and
characterised by at least one of the following:
-Fits when coughing
-Inspiratory whoop or vomiting after coughing
without other apparent cause
DIAGNOSIS CT...
•Observe the child’s cough
•Culture of mucus from back of nose or throat
CLINICAL MANIFESTATIONS
•Symptoms of mild cold e.g. Sneezing, runny
noise, watery eyes, fever, mild cough
•Numerous bursts of rapid coughing. At the
end of these bursts the child takes in air with a
high pitched whoop
•The child may turn blue because of lack of
Oxygen during long bursts of coughing
CLINICAL MANIFESTATIONS CT...
•Vomiting and exhaustion often follow the
coughing fits which are particularly frequent
at night
•The coughing gradually becomes less intense
and stops in two to three weeks
•Production of large amounts of thick mucus
which may be swallowed by babies/children
or seen as large bubbles from the nose
CLINICAL MANIFESTATIONS CT...
•Difficulties in breathing
•Persistent cough after the coughing fits
subside
•Sticky secretions
MANAGEMENT
•Isolation
•Nurse patient in fowlers position
•Maintain good nutrition and hydration
•Provision of oxygen and suctioning of
secretions
•Avoid factors which provoke attacks of
coughing
MANAGEMENT
•Treat with Erythromycin 7.5-12.5 mg/kg body
weight 6 hourly
•Give enough fluids to prevent dehydration
•Encourage breastfeeding
•Maintain nutrition compromised by vomiting
and exhaustion after bouts of coughing
•Give phenobarbitone 5mg /kg /dose 12 hourly
(caution it sedates)
PREVENTION
•Immunisation from the age of 6 weeks
•Maintain cold chain of vaccines
COMPLICATIONS
•Encephalitis
•Aspiration pnuemonia
•Otitis media
•Malnutrition
•Mental retardation if inflammation of the
brain takes place
•Sub-conjuctival haemorrhages due to violence
of the cough
REFERENCES
•Ministry of Health (2002). Expanded
Programme on Immunisation. Malawi Field
Operational Manual. Lilongwe
•Vlok, M.E.(2005) Manual of Community
Nursing: Communicable Diseases Juta & Co
Ltd. Cape Town