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1. Pharmacopoeia
Anofficialpublicationcontainingalistofmedicinal
drugswiththeireffectsanddirectionsfortheiruse.

2. •Theactualprocessofpublishingthefirst
Pharmacopoeiastartedintheyear1944underthe
chairmanshipofCol.R.N.Chopra.TheI.P.listwasfirst
publishedintheyear1946andwasputforthfor
approval.
•I.P.waspreparedbyIndianPharmacopoeiaCommittee
formedin1948.Thetitlesaresuffixedwiththe
respectiveyearsofpublication
•I.P.istheofficialbookofstandardsfordrugstodefine
identity,purityandstrengthforthedrugsimported,
manufacturedforsale,stockedordistributedinIndia.
Indian Pharmacopoeia

3. EditionYearAddendum/SupplementContent
1st Edition1955Supplement 1960 986 Monographs
2nd Edition1966Supplement 1975 890 Monographs
3rd Edition1985
Addendum 1989
1.Consists of 2 Volumes
2.IUPAC system of nomenclature
3.Analytical Techniques were included e.g:
Electrophoresis, Fluorimetry
4.Instrumental Analysis were included e.g:
UV spectroscopy
5.Dissolution of 6 tablets included
6.Limit tests for microbial contamination
Addendum 1991
4th Edition1996
Addendum 2000
1.Consists of 2 Volumes
2.Included 1149 monographs
3.Included new monographs e.g: cream,
gels, eye drops
4.Included method of preparation and
analytical methods like HPLC
5.Include In Process Quality control
Veterinary Products
Vet Supplement 2000
Addendum 2002
Addendum 2005

4. EditionYearAddendum/SupplementContent
5th
Edition
2007Addendum 2008 Consists of 3 Volumes
6th
Edition
2010Addendum 2012 Consists of 3 Volumes
7th
Edition
2014
Addendum 2015 Consists of 4 Volumes with DVD
Addendum 2016
8th
Edition
2018
in 4
Volum
es

5. Indian National Formulary
•Itisareliablereferencebookondrugsformulations
forthepracticingphysicians/clinicians,pharmacists,
clinicalpharmacists,nursesandothersengagedin
healthcareprofession.

6. Indian Pharmaceutical Codex 1953
•Itisabookcontainingdetailedinformationon
indigenousdrugsofIndia.
•indigenousdrugs:Originatingoroccurringnaturally
inaparticularplace.

7. British Pharmacopoeia (BP)
•British Pharmacopoeia is the source of official
standards of drugs in UK and other parts of
the world.
•It was first published by General Medicine
Council and was later done by Pharmaceutical
Commission.
•Since then Pharmacopoeial commission is
reconstituted from time to time and new
editions of British Pharmacopoeia are
published.

8. British Pharmaceutical Codex (BPC)
•BPC was prepared as a reference book to
physicians and dispensing pharmacists in 1907 as
per the Council of Pharmaceutical Society. Since
then subsequent revisions of these books are
published.
•The decision of medicine commission stated that
there should be only one book of standards of
medicine, so BPC was discontinued.
•Later BPC was published as “The Pharmaceutical
Codex” and plans to be encyclopedia.

9. British National Formulary (BNF)
•Formulary is a source of essential information on
drugs and medicines published by
pharmaceutical society of Great Britain and
British Medical Association. • Pharmacological
classification of drugs are given. • It includes
preparations as per Pharmaceutical forms. • It
provides information about actions, uses, dosage
& adverse reactions.

10. United States Pharmacopoeia (USP)
•TheUnitedStatesPharmacopoeiaandtheNational
Formulary(USP-NF)arerecognizedastheofficial
compendiaandareusedasreferencebooksfor
determiningthestrength,quality,purity,packagingand
labelingofdrugsandotherrelatedarticles.
•FirstUSPwaspublishedin1820byUSPharmaceutical
ConventioninEnglishandLatin.Itconsistsof272drugs,
over3400monographsfordrugsubstancesand
products,togetherwithover160generalchaptersthat
describespecificprocedurestosupportmonographtests
andotherinformationaswell.USPalsocontains16
monographsand9generalchaptersonnutritional
supplements.

11. National Formulary (NF) of US
•FirstNationalFormularyofUSwaspublishedin1888by
AmericanPharmaceuticalAssociation.
•USPandNFwascombinedasasinglebookofdrug
standardsasUSP-NF.
•USP-NFrepresents25threvisionofUSP&20threvision
ofNFofficialon2002.FromthenUSP-NFwaspublished
annually.
•NFcoversover3800monographsforexcipientsand
dietarysupplements.

12. International Pharmacopoeia
•TheInternationalPharmacopoeiaispublished
bytheWHOandispracticallyusedin
developingcountries.
•Itwaspreparedtomeettheinternational
uniformityandstandardizationofdrugs.
•InternationalPharmacopoeiawasfirst
publishedin1951inmultilanguages(English,
French,German,Japanese,etc.).

13. European Pharmacopoeia (Ph. Eur.)
•TheEuropeanPharmacopoeia(Ph.Eur.)isthe
legaldocumentforthestandardsofdrugsand
relatedsubstancepreparedbytheCouncilof
Europe.EuropeanPharmacopoeiaVolumeI
waspublishedin1969asfirstEuropean
Pharmacopoeia.Itincludesmorethan2000
specificandgeneralmonographs,including
variouschemicalsubstances,antibiotics,
biologicals,vaccines, immunosera,
radiopharmaceuticals,herbaldrugsand
homeopathicpreparations.

14. Japanese Pharmacopoeia (JP)
•JapanesePharmacopoeiaisestablishedand
publishedtoregulatethepropertiesand
qualityofdrugsbyMinistryofHealth,Labour
andWelfareofJapan.
•Itconsistsofgeneralnotices,rulesforcrude
drugs,rulesforpreparations,generaltests,
processes,apparatusandofficialmonographs.
•Firstpublishedin1886,JPhasbeenrevised
manytimes.

15. Salient features of first edition of IP
•Monographs in Latin as well s in english
•SOS:
•OD: Once in a English
•Was & measures : Metric system

20. Pharmacopoeia
•Pharmacopoeiaistheofficialbookofstandardsfor
drugspreparedbyanycountryorregulatorybodyto
specifythestandardsofidentity,purityandstrength
forthedrugsimported,manufacturedordistributed
throughoutthecountryoraspecificregion.
•Itisabookcontainingcollectionofmonographsand
publishedbyanauthorizedbodylikegovernmentor
Pharmaceuticalsociety.
•ThetermPharmacopoeiacomesfromtheGreek
word“Pharmakon”meaningdrugand“Poieo”
meaningmake,andthecombinationmeansany
formulaorstandardsrequiredtomakeadrug.

21. Pharmacopoeia
•Amonographisacollectionofdetailedinformation
onaparticulardrug,itsdosageformsandmethods
ofanalysis.
•Amonographcontains:
1.Chemicalname 2.Formula
3.Solubility 4.Identification
5.pH 6.Assay
7.Sp.opticalrotation8.LossonDrying
9.Sulphatedash 10.Dose

22. Importance of pharmacopoeia
1.Tomaintaintheuniformityandcontrolthe
standardsofthedrugsavailableinmarket.
2.Avoidadulterateddrugs.
3.Completeinformationondrugsandtheirdosage
forms.
4.Referenceforlaboratory,industryandacademic
institutions.

23. Formulary
•Formulariesarethelistofdrugsorcollectionsof
formulasforthecompoundingofmedicinal
preparations.
•Formulariescontainsmorecomprehensivedetailson
therapeutics.
•Collectivelythesebooksareknownasdrug
compendia.Pharmacopoeias+Formularies=Drug
Compendia

24. Non-official compendia
•Thebooksotherthanofficialdrugcompendiawhich
areusedassecondaryreferencesourcesfordrugs
andotherrelatedsubstancesareknownasnon-
officialdrugcompendia.
•MerckIndex
•Martindale(TheextraPharmacopoeia)