The answer is B. Medications that are classified as weak bases are usually concentrated in breast milk. Contraindicated drugs include anticancer drugs, therapeutic doses of radiopharmaceuticals, ergot and its derivatives (e.g., methysergide ), lithium, chloramphenicol, atropine, thiouracil , iodides, and mercurials . These drugs should not be used in nursing mothers, or nursing should be stopped if any of these drugs is essential. Other drugs to be avoided in the absence of studies on their excretion in breast milk are those with long half-lives, those that are potent toxins to the bone marrow, and those given in high doses long term. However, drugs that are so poorly absorbed orally that they are given (to the mother) parenterally pose no threat to the infant, who would receive the drug orally but not absorb it. Nicotine and alcohol are concentrated in breast milk and should be avoided by mothers who are breast-feeding. Other drugs, including heparin, acetaminophen, insulin, diuretics, digoxin, β- blockers, penicillins , cephalosporins , most over-the-counter cold remedies, amitriptyline, codeine, and ibuprofen, do not show up in significant amounts in breast milk . Some oral contraceptives can depress lactation (particularly large-dose, estradiolcontaining birth control pills), but in most cases are considered safe.