Subject Description
•Biology I is a Science, Technology, Engineering and Mathematics
(STEM) Specialized Subject taken in the first half of Grade 11.
•Learners go on a journey geared toward the deeper understanding
and appreciation of life processes at the cellular and molecular
levels previously introduced in Grades 7-10. They will also apply
basic chemistry and physics principles as they examine the
transformation of energy in organisms.
Let’s Revisit BIOLOGY as a subject
•Reflectuponyourpastexperiencesduringyourjuniorhighschool
yearswhenyouwereexposedtolessonsfocusedonbiology.
•Ona1wholeyellowpaper,compileacomprehensivelistofthe
biologytopicsthatyoucanstillrecallfromyourjuniorhighschool
education.
CELL: THEORY, STRUCTURE AND FUNCTION
MELC’s
1.Explainthepostulatesofthecelltheory.(STEM_BIO11/12-Ia-c-1)
2.Describethestructureandfunctionofmajorandsubcellular
organelles.(STEM_BIO11/12-Ia-c-2)
What are CELLS?
•Cells are the basic building blocks
of all living things.
•The human body is composed of
trillions of cells. They provide
structure for the body, take in
nutrients from food, convert those
nutrients into energy, and carry
out specialized functions.
•Cells also contain the body’s
hereditary material and can make
copies of themselves.
The CELL Theory
•How/in what way can we observe
cells?
Advanced Compound Microscope
Magnification of up to 1000x
The CELL Theory
•Who invented the first microscope?
Zacharias Janssen –1600
-Dutch spectacle maker
The Scientists behind the CELL Theory
•Robert Hooke
•Antonievan Leeuwenhoek
•Robert Brown
•Matthias Schleiden
•Theodor Schwann
•Rudolph Virchow
Robert Hooke
•Advancements in the microscope
were crucial for the discovery of
cells.
•Robert Hooke improved the
compound microscope in 1665.
•Hooke'
lenses and a stage light for
illumination and magnification.Robert Hooke
Robert Hooke
•Hooke observed something
fascinating when he examined
cork under the microscope.
•Hooke documented his
observations in his book,
Micrographia.
•He referred to the structures in
cork as "cells" due to their
resemblance to monastery cells.
Robert Hooke’s Microscope
Antonievan Leeuwenhoek
•In 1674 Dutch scientist Antonie
van Leeuwenhoek published his
observations on tiny living
organisms which he named
animalcules.
Antonievan Leeuwenhoek
•It was believed that
Leeuwenhoek was the
first to observe under his
microscope the structure
of an Erythrocyteof
different animals as well
as a sperm cell.
Robert Brown
•One of the leading botanists in
his time, Robert Brown in 1831
was able to compare diverse
kinds of plant specimens under
the microscope.
•He markedly indicatedthat there
is a common thing about them-
they are all composed of cells, and
inside the cell is a dark dense spot
which he termed as the nucleus.
Matthias Schleiden
•He is a German botanist who in
1838 concluded that all plant
parts are made of cells.
Theodor Schwann
•He is a physiologist and
histologist and a close
friend of Schleiden.
•In 1839, he stated that all
animal tissues are
composed of cells, too.
Rudolf Virchow
•In 1855, the third tenet of
Schwann were replaced by the
Rudolph Virchow’s powerful
dictum, Omnis cellulae cellula,
“All cells only arise from pre-
existing cells”.
The CELL Theory
•The discoveries made by Hooke, Leeuwenhoek, Schleiden,
Schwann, Virchow, and others led to the formulation of the cell
theory.
•This theory can be summed up into three basic components:
(1)all living things are composed of one or more cells;
(2)the cell is the basic unit of life; and
(3)all cells arise from preexisting cells.
The CELL Structures and Functions
•The cells are the building blocks of life just as atoms are the
basic building blocks of all matter.
•Each cell contains materials that carry out basic life processes.
•Cell structures can only be observed under high magnification
electron microscope.
The CELL Structures and Functions
The CELL Structures and Functions
•A cell consists of three parts:
•the cell membrane,
•the nucleus, and, between the two,
•the cytoplasm.
•Within the cytoplasm lie intricate arrangements of fine fibers
and hundreds or even thousands of miniscule but distinct
structures called organelles.
The CELL Structures and Functions
These organelles perform a
variety of functions like:
•production of proteins,
•storage of important materials,
•harvesting energy,
•repairing cell parts,
•digestion of substances, and
•maintaining the shape and
structure of the cell.
The CELL Structures and Functions
The structures and functions of the cell organelles are categorized
into four:
•Manufacturing
(Nucleus, Ribosome, Rough and Smooth ER, Golgi
apparatus)
•Breakdown (Lysosomes, Vacuoles, Peroxisomes)
•Energy Processing (Mitochondria, Chloroplasts)
•Structural Support, Movement, and Communication
(Cytoplasm, Cytoskeleton, Centrioles, Cell Membrane, Cell
Wall, Chromatin)
Ribosome
Function:
•Protein synthesis
•This process involves
decoding the sequence of
nucleotides in mRNA and
assembling the
corresponding amino acids
in the correct order to form
a polypeptide chain, which
ultimately folds into a
functional protein.
Rough Endoplasmic Reticulum (RER)
Surrounded by ribosomes
Function:
•synthesis of membrane
lipids and proteins,
secretory proteins, and
hydrolytic enzymes;
•formation of transport
vesicles
Smooth Endoplasmic Reticulum (SER)
Surrounded by ribosomes
Function:
•Lipid synthesis;
detoxification in liver cells
Golgi Apparatus
Function:
•Modification and transport
of macromolecules;
•Formation of lysosomes
and transport vesicles
Lysosomes
Function:
•Digestion of ingested food,
bacteria, and a cell’s
damaged organelles and
macromolecules for
recycling