LEARNING OUTCOMES
Define premature labour
Explain the diagnosis of premature
labour
Discuss the predisposing factors to
premature labour
Explain the prevention of premature
labour
Explain the management of premature
labour
Definition
Labour that occurs before 37 completed
weeks of pregnancy regardless of birth
weight
Presence of contractions of sufficient
strength and frequency to effect
progressive effacement and dilatation of
the cervix
Birth prior to 20 weeks is an abortion
Prematurity continues to be the major
perinatal and neonatal problem causes of
fetal morbidity in Malawi
Most mortality and morbidity is experienced
by babies born before 34 weeks gestation
Diagnosis
Prompt diagnosis is difficult because many of its
symptoms are also common in normal pregnanc
Abdominal pain
Pelvic pain
Menstrual like cramps
Pelvic pressure
Onset of regular uterine contractions
Progressive change in cx dilatation & effacement
Vaginal bleeding
Criteria for diagnosis of
preterm labour
Gestation 28-37 weeks
Documented uterine contractions
Documented cervical changes ( effacement
and dilatation)
Predisposing factors
Poverty/social deprivation
Marital status
Overworking
Psychological distress
Prevention
Identification of patients at risk and their
referral for medical investigation and
management
Patient identification for those at risk i.e.
importance of hygiene and cleanliness
Special investigations for the cause, if
patient has any history of preterm labour
or abortion
Treatment of any local infections
Medical management
Management is controversial and depends
on many circumstances and on the
facilities available
Controversial issues include:
Whether to suppress labour or not
Whether to use steroids to accelerate fetal
lung maturity
Indications for allowing labour to
progress
Fetus is more than 36 weeks
There is placental insufficiency
There is serious maternal disease
Gross fetal malformation
Cervix has dilated more than 3-4 cm
The fetus is distressed, dead,
Tocolytics (uterine antispasmodics)
The intervention aims to delay delivery
until the effect of corticosteroids has
been achieved
Attempt tocolysis if
Gestation is less than 37 weeks
Cervix is less than 3 cm dilated
There is no amnionitis, pre-eclampsia or
active bleeding
There is no fetal distress
Drugs used
Currently administered drugs:
Nifedipine 10-20 mg OD or 12 hourly
for suppressing labour
Drugs not being used currently
Salbutamol (reduces uterine activity)
Magnesium sulphate
Steroids
These are indicated if gestational age is not
less than 28-34 weeks and membranes are
intact
Given for lung maturity of the baby before
birth
Betamethasone 12mg IM 2 doses 12 hours
apart or
Dexamethasone 12mg IM 12hourly for 4
doses for surfactant/maturing lungs
Conservative management
First determine if it is true labour
Monitor contractions
Complete bed rest in hospital
Sedation may be used to relieve anxiety
No vaginal examination, only a sterile
speculum examination ( if done keep to the
minimum)
Conservative management
Administration of drugs on doctors
orders
Monitoring maternal condition with 4
hourly temperature and other vital signs
Monitor progress of labour
Monitor pads for liquor
Maintain strict output and intake chart
Conservative management
Preserve the membranes to prevent
infection
Adequate pain relief measures
Close fetal and maternal monitoring
Advise woman to lie on left lateral
position to facilitate maternal fetal
circulation
Labour and delivery
If the labour progresses despite
attempt to control it, inform the doctor
Continue to monitor labour progress,
fetal condition, maternal condition and
manage as in normal labour
Stop all labour suppressing drugs
Labour and delivery
Paediatrician to be present at delivery
Avoid rapid delivery of the baby with
careful delivery of the head
Avoid compression and decompression of
the fetal head
There should be skilled resuscitation
team available
BABY
Keep baby warmth-very essential for
preterm baby
Handle baby very gently
Administer oxygen, if required
Perform suctioning of air passages
where necessary
Transfer baby to nursery ward