PRESENTATION OF FETAL GENE THERAPY. PDF.

fetal gene therapy

1. THE FUTURE OF MEDICIN
FETAL GENE TERAPY

2. WHAT IS FETAL THERAPY ?
Also known as fetal Treatment, it is
the diagnosis and treatment of
abnormalities in utero .

3. It Can be classified into
1-Fetal Gene Therapy
2-Fetal Stem Cell Therapy
3-Fetal Blood and Tissue Sampling
4-Pharmacological Therapy
5-Fetal Surgery

4. Fetal gene therapy
Is a technique that modifies
a fetal’s gene to treat or cure
diseases.

5. Prenatal Testing Screening test
•First trimester screening
•Fetal echocardiogram
•Amniocentesis
•Second trimester screening

6. Mechanism of fetal gene therapy
•In general, is addition of a new gene to the cell to
compensate for a mutated gene by viral vectors (AAV).
•its mechanism is a working gene is transferred
into the cell by viral vectors to start produce a
normal protein

7. There is two ways to give gene therapy
❖In vivo:
Injection of gene inside the body
❖Ex vivo:
Injection of gene outside the body
(in laboratory)

8. What can be accomplished by gene
therapy ?
Scientists are looking to treat many genetic diseases
through fetal gene therapy such as :-
5-Gaucher’s disorder
2-SCID
3-Dawn’s syndrome
4-Haemophilia
1-XLHED

9. ❖In2018studypublishedinTheNewEnglandJournalof
Medicineresearchersusedfetalgenetherapytoprevent
XIHEDaninheriteddisorderinthreebabies.
❖The babies were around 2 years old when paper was
published and seemed to be okay.

10. Risks of Gene Therapy
1-the most common problem is a lack of
effectiveness.
2-(Unwanted Immune System Reaction )
3-(Wrong Target Cell)
4-(Infection Caused by Viral Vector)
5-(possibility of unintended genetic changes)
6-(Possible Tumor)

11. Conclusion
itcanbesaidthatfetalgenetherapyrepresentsa
tremendousdevelopmentinthefieldofmedicine.Itopens
newdoorsfortreatingandeliminatinggeneticdiseasesfrom
theearlystageofpregnancy.Withtheadvancementof
technologyandresearchinthisfield,wehopethatthis
treatmentwillbecomeavailabletoeveryoneinthefuture.

12. •فيشرلا رعم ركبوب أ ءلاو
•يديع�ا دمحم ةي أ
•قلا�ا بايه ا ىؤر
•يملح نب ليع ةشئاع
• يم شخ دحم أ ةيملح
•بئاتلا دحم أ ةباجت سا
•يديلحما حلاص ةراس
•ليمرلا ليع ةراس
•شد سياس دلايم ى
•يرتلا جرف ايند
فاشر ا تتح:د .ينم أ فيزوج
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