9.6millionpeoplediefromcancerevery
year.
At least one third of common cancers are
preventable.
Cancer is thesecond-leading
causeof death worldwide.
70%ofcancerdeathsoccurinlow-to-middle
incomecountries.
Upto3.7millionlivescouldbesavedeachyear
byimplementingresourceappropriatestrategies
forprevention,earlydetectionandtreatment.
A disease which occurs when changes in a group of normal
cells within the body lead to uncontrolled, abnormal
growth forming a lump called a tumour –true of all
cancers except
leukaemia (cancer of the blood).
If left untreated, tumours can grow and spread into the
surrounding normal tissue, or to other parts of the body
the bloodstream and lymphatic systems, and can affect the
digestive, nervous and circulatory systems or release
hormones that may affect body function.
Division of
Tumours
Benign Malignant Precancerous
Benign
•grows quite slowly,
•do not spread to other
parts of the body
• usually made up
of cells quite similar to
normal or healthy cells.
• cause a problem if
they grow very large,
becoming uncomfortable
or press on other organs
-for example a brain tumour
inside the skull.
•are not cancerous
Malignant
•Grows faster than benign
tumours
• ability to spread and
destroy neighbouring tissue.
•Cells of malignant tumours can
break off from the main
(primary) tumour and spread to
other parts of the body through a
process known
as metastasis.
• invades healthy tissue
at the new site they continue to
divide and grow.
•These secondary sites are known
as metastases and the condition
is referred to as metastatic
cancer.
Precancerous
•describes the condition
involving abnormal cells
which may (or is likely to)
develop into cancer.
•Arises from the epithelial cells
•Invade surrounding tissues, organs, metastasis to the
Lymph nodes and other area of the body
•Common forms of cancer are breast , prostrate, lung
and colon
Carcinoma
•malignant tumour of the bone or soft tissue (fat,
muscle, blood vessels, nerves and other connective
tissues that support and surround organs).
• common forms of sarcoma are
leiomyosarcoma, liposarcoma and osteosarcoma
Sarcoma
•Ariseinthecellsoftheimmunesystem
•Lymphomaisacancerofthelymphaticsystem
•Myeloma(ormultiplemyeloma)startsintheplasma
cells,atypeofwhitebloodcellthatproduces
antibodiestohelpfightinfection.
Lymphoma
&Myeloma
•Occurs in the white blood cells and bone marrow,
the tissue that forms blood cells.
•There are several subtypes; common are lymphocytic
leukaemia and chronic lymphocytic leukaemia
Leukemia
•central nervous system cancers.
•Some are benign while others can grow and
spread.
Brain and
Spinal Cord
⦿Modifiable risk factors
Alcohol
Being overweight or
obese
Diet and nutrition
Physical activity
Tobacco
Ionizing radiation
Work place hazards
Infection
⦿Non-modifiable risk
factors
Age
Cancer-causing
substances
(carcinogens)
Genetics
The immune system
Unusual lumps or swelling –cancerous
lumps are often painless and may increase
in size as the cancer progresses
Coughing, breathlessness or difficulty
swallowing –be aware of persistent coughing
episodes, breathlessness or difficulty
swallowing
Changes inbowelhabit
–such as constipation
and diarrhoea and/or
blood found in the stools
Unexpected bleeding –
includes bleeding from the
vagina, anal passage, or blood
found in stools, in urine or
when coughing
Unexplainedweightloss–a
largeamountofunexplained
andunintentionalweightloss
overashortperiodoftime(a
coupleofmonths)
Fatigue –which shows itself as
extreme tiredness and a severe lack
of energy. If fatigue is due to
cancer, sufferers normally also have
other symptoms
Pain or ache –includes
unexplained or ongoing pain,
or pain that comes and goes
Newmoleorchangestoamole–look
forchangesinsize,shape,orcolourand
ifitbecomescrustyorbleedsoroozes
Complications with urinating –
includes needing to urinate
urgently, more frequently, or being
unable to go when you need to or
experiencing pain while urinating
Unusual breast changes –
look for changes in size, shape
or feel, skin changes and pain
A sore or ulcer that won’t heal
–including a spot, sore wound or
mouth ulcer
Appetite loss –
feeling less hungry
than usual for a
prolonged period
of time
Heartburnorindigestion
–persistent or painful
heartburn or indigestion
Heavynightsweats–beawareof
veryheavy,drenchingnightsweats
Over a third of all cancers can be prevented by reducing your exposure to risk
factors such as
tobacco, obesity, physical inactivity, infections, alcohol, environmental
pollution, occupational carcinogens and radiation.
Prevention of certain cancers may also be effective through vaccination
against the Hepatitis B Virus (HBV) and the Human Papilloma Virus (HPV),
helping to protect against liver cancer and cervical cancer respectively.
Reducing exposures to other carcinogens such as environmental pollution,
occupational carcinogens and radiation could help prevent further cancers.
There are a number of cancers which can be
identified early which helps to improve the chances
of successful treatment outcomes, often at lower
costs and with fewer (or less significant) side effects
for patients.
There are cost-effective tests that help detect
colorectal, breast, cervical and oral cancers early and
further tests are being developed for other cancers.
Treatment
depends on
the type of
cancer
where cancer is,
how big it is,
whether it has
spread
Generalhealth.
Typesof
Treatment
Surgery
Chemo
therapy
Radio
therapy
Hormone
therapy
Immunot
herapy
Gene
therapy
Surgery
⦿ If a cancer has not metastasized (spread), surgery can remove the
entire cancer which may completely cure the disease.
Often, this is effective in removing the prostate or a breast or testicle.
Radiotherapy
⦿Radiationtreatmentorradiotherapyuseshigh-energyraystoreducea
tumourordestroycancercellsasastand-alonetreatmentandinsome
casesincombinationwithothercancertreatments.
Immunotherapy
Immunotherapyusesthebody'sownimmune
systemto fightthe cancer tumour.
Immunotherapy may treat the whole body by giving an agent that
can shrink tumours.
Hormone therapy
Severalcancershavebeenlinkedto sometypesof
hormones, including breast and prostate cancer.
Hormone therapy works to change hormone production in the
body so that cancer cells stop growing or are killed completely.
Gene therapy
The goal of gene therapy is to replace damaged genes with ones
thatworktoaddressarootcauseofcancer:damagetoDNA.
Othergene-basedtherapiesfocusonfurtherdamagingcancer
cellDNAtothepointwherethecelldestroysthemselves.However,
genetherapyisnewandhasnotyetresultedinanysuccessful
treatments.
Survivorship
Survivorship focuses on
healthand the physical,psychological,socialand economic
issuesaffecting people after the end of the primary treatment for cancer,
including people who have no disease after finishing treatment,
people who continue to receive treatment to reduce the risk of the cancer coming
back and
people with well controlled disease and few symptoms, who receive treatment to
manage cancer as a chronic disease.
Survivorship care includes issues related to
follow-up care,
the management of late side-effects of treatment,
the improvementof qualityof lifeand
psychologicaland emotional health.
Survivorshipcareincludesalsofutureanticancer
treatment where applicable.
Family members, friends and caregivers should also be considered as part
of the survivorship experience.
Awareness,
understanding, myths and
misinformation Access to
information and knowledge
about cancer can empower
us all.
Prevention and risk reduction
Over one third of cancers are
preventable, which means we all
can reduce our cancer risk.
Equity in access to cancer services
Life-saving cancer diagnosis,
treatment and care should be equal
for all –no matter where you live,
what your income, your ethnicity or
gender.
Government action and
accountability
Governments can influence many
of the levers to reduce and prevent
cancer.
Beyond physical: mental and
emotional Impact
The impact of cancer goes far beyond
physical health, impacting the mental
and emotional wellbeing of patients
and their caregivers.
Saving lives saves money
The financial impact on nations,
individuals and families have a huge
impact on sustainable economic and
human development. By focusing on
saving lives, we can also save money
Reducing the skills gap
A shortage of skilled healthcare
workers is one of the greatest
barriers in delivering quality cancer
care.
Working together as one
By joining forces, we help to
strengthen efforts that stimulate
powerful advocacy, action and
accountability at every level.
The Cancer Atlas: History of Cancer
⦿Explore a timeline of the history of cancer from
BCE to 2011
⦿National Cancer Institute: Dictionary of
Cancer Terms
⦿Cancer terms explained
International Agency for Research on Cancer:
Global Cancer Observatory
⦿An interactive web-based platform presenting
global and national cancer statistics to inform cancer
control and research
World Health Organization: Cancer Country
Profiles
Synthesized national cancer data by country,
including data on mortality, incidence and risk
factors
The Cancer Atlas: Risk Factors
⦿Understanding risk factors and causes of
cancer
The Cancer Atlas: How to take action
⦿Discover the opportunities for controlling
cancer World Cancer Research Fund: Facts
and Figures on specific cancers
⦿World Cancer Research Fund International is
the world’s leading authority on cancer
prevention research related to diet, weight and
physical activity
World Cancer Research Fund International: Cancer
prevention recommendations
⦿Explore the recommendations on helping to prevent
cancer
Cancer.Net: Individual guides on each type of cancer
⦿Access over 120 individualized and oncologist-
approved guides
Cancer.Net: Questions to ask your doctor
⦿Find guidance on what to ask your health team, as
approved by the American Society of Clinical Oncology
⦿National Comprehensive Cancer Network:
Cancer Staging
⦿Understand what cancer stages mean
⦿National Cancer Institute: Types of treatment
⦿Understand the treatment options for cancer
UICC and Bupa: Working with cancer
⦿A resource for both employers and
employees
International Psycho Oncology Society:
Survivorship
⦿Download a practical guide for patients
and caregivers
Medical News Today: Most recent research
breakthroughs
⦿Read about how close we are to finding
more effective treatments
Union for International Cancer Control:
Members
⦿Find a national cancer organization near
you