hypothermia is one of the major causes of neonatal death
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By DrAbdurahmanS.
Moderator DrHana A.(pediatric surgeon)
INTRODUCTION
THERMOREGULATION
◦HEAT PRODUCTION
◦HEAT LOSS
◦Thermoregulation and Anesthesia
HYPOTHERMIA
PERIOPERATIVE HYPOTHERMIA PREVENTIVE MEASURES
COMPLICATION OF PERIOPERATIVE HYPOTHERMIA
REFERENCES
Maintaining a neutral thermal environment is one of
the key physiologic challenges that a newborn must
face after delivery
In early 1900s
◦Realized warm environment is essential
Last decades
◦Improved care of newborns in developed world
◦Still common problem in developing countries
Thermal care is central to reducing morbidity and
mortality in newborns.
Thermoregulation
◦The ability to balance heat production and heat loss in
order to maintain body temperature within a certain
normal range(36.5-37.5ºc)
Goals
◦Maximize metabolic efficiency
◦Reduce oxygen use
◦Protect enzyme function
◦Reduce calorie expenditure
Thermoneutral zone:
◦The range of ambient temperature required for the
infant (for each gestational age and weight) to keep a
normal body temperature and a minimal basal
metabolic rate
Extreme environmental temperature variations
◦overcome this effective thermoregulatory function
lead to heat-or cold-related illnesses
Radiation
convection
Evaporation
Conduction
Heat loss occurs from
energy needed to vaporize
liquids
◦skin,lung,mucosa and serosa
Accounts major heat
loss…50%
Depends on
◦The exposed body surface area
◦Relative humidity of the
ambient air
◦The speed of the wind
Heat loss to the nearby cold
objects with out physical
contact
Major source of heat loss in
most surgical patients(60%)
Depends on
◦The T differences
◦The body exposed to the
environment
◦Distance between two surfaces
◦The skin blood flow
Heat transfer from warm to
cool objects with direct contact
Accounts 5%
Depends on
◦Area of body exposed
◦Relative difference in temperature
◦Thermal conductivity
Special type of conduction heat
loss through moving gases
Accounts 15%
Second most common heat loss
in anesthetized pt
Depends on
◦The temperature difference
◦The speed of air
Proportional to the square root of air
speed
Cold Items on Bed
Cold Walls
Cold Room Temp.
Radiation
Cold Blankets
Cold X-ray plates
Cold Scale
Conduction
Passing Traffic
Oxygen left on
Bed Near Air Vent
Convection
Tachypnea
Bath
Wet Diaper
Evaporation
Baby d
During pregnancy
◦Maternal mechanisms maintain the intrauterine
temperature
After birth
◦The newborn must adapt to their environment by the
metabolic production of heat
Primary source of heat in the newborn
◦Non -shivering thermogenesis
◦Metabolic processes
◦Voluntary muscle activity
◦Involuntary muscle activity (shivering thermogenesis)??
◦Peripheral vasoconstriction
Metabolism of brown adipose tissue
◦Initiated in hypothalamus
◦Sympathetic nervous system
◦Norepinephrine release at the site of brown fat
◦Non-shivering thermogenesis is initiated and brown
fat is burned for energy to keep the body temperature
stable
This is the infant’s initial response
3
Brown fat is an
energy source for
infants
It can be found:
◦Near Kidneys and
adrenals
◦Neck, mediastinum,
scapular, and the
axilla areas.
Can not be replaced
once used
In full term infants
◦4 % -10% of adipose deposits
In preterm infants
◦Not be found until 26-30 weeks gestation
◦Then only in small amounts
Disappears 3-6 months after birth
◦In cold stressed infants
Disappears sooner
Hypoxia causes impairment of brown fat
metabolism
5
A large surface area-to-body mass ratio
Decreased subcutaneous fat
Greater body water content
Immature skin leading to increased evaporative
water and heat losses
Poorly developed metabolic mechanism for
responding to thermal stress (e.g. no shivering)
Premature
SGA
Neuro problems
Endocrine
Cardiac / respiratory problems
Large open areas in the skin
Sedated Infants
Drug exposure
8
Anesthesia-induced inhibition of central
thermoregulation
Internal redistribution of heat from the central
to the peripheral compartment
Reduction in metabolic heat production
Increased exposure to the environment
◦up to 90% of heat loss occurs via skin mainly by radiation and convection
Patterns of body temperature
after general anesthesia
1.Internal redistribution of heat
2.Thermal imbalance
3.Thermal steady state (plateau or
rewarming)
Definition:
It is a condition characterized by lowering of
body temperature than 36.5°C.
Could be classified based on:
◦Causes:
Primary and secondary
◦Severity:
Mild( 35-36.4ºc)
Moderate(32-34.9ºc)
Severe (<32ºc)
Hypoxemia
Hypoglycemia
Respiratory & metabolic acidosis
Inhibition of surfactant production
pulmonary blood flow
pulmonary vascular resistance compromises the
delivery of oxygen at the cell level
risk of developing PPHN
Mild hypothermia
◦Skin-to-skin contact
In a warm room
At least 25°C
◦Covering of head with
cap
◦Cover mother and
newborn with warm
blankets
Moderate hypothermia
◦Under a radiant heater
◦In a warmed incubator
◦In a heated water-filled
mattress
◦skin-to-skin contact with the
mother
Severe
◦Warm incubator
◦Skin to skin contact in warm room
Warm chain
1)Warm delivery room
2)Immediate drying
3)Skin-to-skin contact
4)Breast-feeding
5)Bathing and weighing postponed
6)Appropriate clothing/bedding
7)Mother and baby together
8)Warm transportation
9)Warm resuscitation
10)Training and awareness raising
RADIANT HEAT LOSS
◦Avoiding placement of incubators,
warming tables and bassinets near cold
windows, walls, air conditioners, etc..
◦Placing a knit hat on the infant’s head
◦Wrapping tiny babies in saran or “bubble”
wrap
◦environmental temperature
6
EVAPORATIVE HEAT LOSS
◦Keeping the neonate and his/her
environment dry
◦Drying the baby immediately after
delivery
◦Placing preterm or SGA infant in
occlusive wrap/bag at delivery
◦Delay bath until temperature is
stable
7
CONDUCTIVE HEAT LOSS
◦Placing a warm diaper or blanket
between the neonate and cold surfaces
◦Placing infant on pre-warmed table at
time of delivery
◦Warming all objects that come in
contact with the neonate
◦Admitting infant to a pre-warmed
room
◦Skin to skin contact
8
CONVECTIVE HEAT LOSS
◦Providing warm ambient air temperature
Placing infants less than 1500 grams in
incubators
Keeping portholes of the incubator closed
Warming all inspired oxygen
On open warmers keeping sides up and
covering infant if possible
Using Infant Servo Temperature Control
9
Preoperative warming
◦To keep a patient comfortably warm
◦To prevent phase I hypothermia
◦Techniques
Active-with forced air warming
Passive-with passive insulation
Warm blanket
Socks
Warm circulating water mattress
Head covering
◦Duration ???
30’ to 1hr
Operating room warming
◦Reduces the temp. gradient
◦Ideally
For preterm …minimum 29ºc
Term…..27ºc
Adult……21ºc
◦Relative humidity
40-60%
Using warm fluids
◦Both IV and irrigations
Humidified and warm inspired gases
◦With HME device.
Appropriately covered during any transport
◦Older children and adults
A warm blanket may be sufficient
◦Neonates and premature babies
Transport in a prewarmed incubator, or
Chemical heating pads
Most commonly used to warm patients in post
anesthesia recovery room
◦Forced air blankets
◦Radiant heaters
Increased intraoperative blood loss and
transfusion
Adverse cardiac events
Prolonged stay in RR and hospital
Delayed surgical wound healing and high rate of
infection
Cold induced coagulation dysfunction
Prolonged drug metabolism
CORAN PEDIATRICS SURGERY 7TH EDITION
Atlas procedures in neonatology
Pediatric Anesthesia : Bruno Bissonnette
Thermal protection of the newborn: a practical
guide. WHO/RHT /MSM/97
Uptodate