Progenitor cells. muskan

What are Progenitor cells?
Comparison Between Progenitor and Stem cells.

1. PROGENITOR CELLS Submitted To : Dr. Geeta Singh Submitted By: Muskan Pawar Department of Biomedical Engineering Roll No. 13001007011 Subject :Tissue Engineering B.Tech . Biomedical Engineering 4 th Year(8 th Semester)

2. Progenitor Cell : Progenitor Cells are cells with the capability of differentiating into several different cell types as needed. Progenitor Cell is a biological cell that is like a Stem Cell , but is already more specific than a stem and is pushed to differentiate into its target cell. Progenitor means a direct ancestor or an originator or founder of a future development. These cells are found in numerous locations within the body and are being produced all the time to keep up a continuous supply of fresh cells.

3. Stem Cells: A simple cell in the body that is able to develop into any one of various kinds of cells(such as blood cells , skin cells , etc ). Or An unspecialized cell capable of perpetuating itself through cell division and having the potential to give rise to differentiated cells with specialized functions.

4. Example of Progenitor Cell:  An example of a progenitor cell is an undifferentiated blood cell produced in the bone marrow. The cell could mature into any number of blood cells, but it cannot grow up to be another cell type like a muscle cell or a  nerve cell.

5. Difference between Stem Cell and Progenitor Cell Stem Cell On The Basis of Description: Stem Cells are reserve cells that have the ability to change into many different types of cells and grow indefinitely. They have the potential to create many new different cells that can help replace dying and/or damaged cells. Stem cells also have the potential to create new tissue and even whole organs from just a few stem cells. Progenitor Cell On the Basis of Description : Progenitor cell are very similar to stem cells. They are biological cells and like stem cells, they too have the ability to differentiate into a specific type of cell. However, they are already more specific than stem cells and can only be pushed to differentiate into its "target" cell.

6. Stem Cells: On the Basis of Types: Four main types of stem cells: Adult or somatic stem cells Fetal stem cells Embryonic stem cells Induced stem cells Progenitor Cells: On the Basis of Types: Many , as each "target" cell has its own progenitor cell. Some of the types include: Satellite cells found in muscles . Bone marrow stromal cells Pancreatic progenitor cells Angioblasts or endothelial progenitor cells (EPC) Blast cells

7. Blood Cell Production:

8. Stem Cells: Features: Multiply by cell division to replenish dying cells and regenerate damaged tissues. Generate all the cell types of the organ from which they originate. Potentially regenerating the entire organ from a few cells. Progenitor Cells: Features: Tendency to differentiate into a specific type of cell, but is already more specific than a stem cell and is pushed to differentiate into its "target" cell. Can divide only a limited number of times.

9. Stem Cells: Benefits: They have the potential to increase healing and for potentially regenerating an entire organ from a few cells.  They are investigated in treatment of: Diabetes , Wound Heeling , Anti-cancer , Baldness ,Replace missing teeth, Repair hearing , Restore vision Progenitor Cells: Benefits: They act as a repair system for the body . They replenish special cells, but also maintain the blood, skin and intestinal tissues. Progenitor cells can be activated in case of tissue injury, damaged or dead cells. It leads to the recovery of the tissue.

10. Stem Cells: Controversy : The use of human adult stem cells in research and therapy is not considered to be controversial. The use of human embryonic stem cells in research and therapy is controversial as they are derived from human 5 day old embryos generated by IVF (in vitro fertility) clinics designated for scientific research. Progenitor Cells: Controversy: The progenitor cells are not subject to controversy.

11. References: http:// www.wisegeekhealth.com/what-are-progenitor-cells.htm http:// www.thefreedictionary.com/progenitor https:// www.merriam-webster.com/dictionary/stem%20cell http:// www.differencebetween.info/difference-between-stem-cell-and-progenitor-cell