Proliferative phase

1. PROLIFERATIVE/FOLLICULAR/PREOVULATORY PHASE Starts at the end of menstrual phase Lasts from 5 th /6 th day to 14 th day of cycle Ovarian events : Maturation of follicles Till ovulation

2. DEVELOPMENT OF FOLLICLE

3. Endometrial events: Estrogenic phase Proliferation of all elements Glands Tubular lie perpendicular to surface Lined by columnar epithelium with nuclei at base with evident mitoses and epithelium of 1 gland is continuous with another

4. Stromal cells Spindle shaped Evidences of mitoses Compact with expansion of stromal ground substance Blood vessels Spiral arteries Evidence of sub epithelial congestion Later stages intense vascularity with more coiled and spiral arteries

5. Thickness 3.5-5mm Phase ends with ovulation of secondary oocyte