Properties of colloids in Physical Pharmaceutics

Colloids are essential in physical pharmaceutics, characterized by fine particles dispersed in a continuous medium, typically ranging from 1 nm to 1 µm in size. This small particle size enables them to remain suspended and prevents sedimentation, a property reinforced by Brownian motion, where particles move randomly due to collisions with surrounding molecules. Colloids also exhibit the Tyndall effect, scattering light and allowing for their characterization. Their stability is influenced by surface charge and zeta potential, which help predict interactions between particles. Additionally, colloidal dispersions can have increased viscosity, affecting drug delivery and absorption, and can exert osmotic pressure, crucial for drug formulation. They are capable of adsorbing molecules from their environment, further impacting their function in drug delivery systems. Understanding these properties is vital for developing effective pharmaceutical formulations, such as suspensions, emulsions, and vaccines, which rely on the unique behavior of colloids to enhance solubility, stability, and therapeutic efficacy.

1. PROPERTIES OF COLLOIDS P. DAKSHINESH B. Pharm (IV SEM) Nandha college of pharmacy.

2. 1. OPTICAL PROPERTY           LIGHT SCATTERING           TYNDALL EFFECT           TURBIDITY           LIGHT SCATTERING 2. KINETIC PROPERTY           BROWNIAN MOTION           DIFFUSION           SEDIMENTATION           VISCOSITY 3. ELECTRICAL PROPERTY           ELECTROPHORESIS