Protease enzyme

Protease Enzyme and their functions, sources, classification and applications.

1. “PROTEASE ENZYME”
By
Syeda Sadaf Wajahat

2. What are Proteases?
▪Proteasesaretheenzymeswhichbreakdown
theproteinsintosmallerpolypeptidesoramino
acids(proteolysis).
▪Proteases,asalsoknownasaspeptidasesor
proteinases.

3. Functions of
Proteases
•Digestionandcatabolismofproteins.
•Bloodcoagulation.
•Celldivision,growth,apoptosisandmigration.
•Proteinrecyclingandtransportacrossmembranes.
•Mediateimmuneresponse.
•Woundhealingandmusclesoreness.
•Video:
https://www.youtube.com/watch?v=DvqZea4dq5E

4. Sources of Proteases
Sources
Plants
(e.g. Papain,
Bromelain)
Microorganisms
(e.g. Subtilisin,
Thermolysin)
Animals
(e.g. Trypsin,
Pepsin)

5. Classification of Proteases

6. On the basis of
reaction they catalyze

8. On the basis of site of enzyme
action

10. On the basis of pH

11. pH
Acidic
AlkalineNeutral

12. On the basis of mechanism of
catalysis

13. Threonine
peptidase
Asparagine
peptidase
Aspartic
peptidase
Cysteine
peptidase
Glutamic
peptidase
Metallo-
peptidase
Serine
peptidase

14. Applications of Proteases