Retinitis Pigmentosa and vitreous by Dr H N Sowbhagya.pptx

power point presentations prepared for MBBS Graduates teaching. helps in easy explanation of the sheduled module in the teaching programmes

1. Retinitis Pigmentosa and vitreous DR H N SOWBHAGYA PROFESSOR DEPARTMENT OF OPHTHALMOLOGY SSIMS and RC

2. INTRODUCTION Chris McCausland : stand-up comedian and actor with retinitis pigmentosa . Retinal dystrophy occurs in 1 in 5000 populations Males, bilateral Hereditary disorder affecting the photoreceptor Sporadic Inherited disorder Autosomal dominant RP Autosomal recessive X- linked recessive

3. Pathogenesis Apoptosis of rods and cones Type 1- rods Type 2- combined rods and cones

4. Clinical features Symptoms Night blindness Age of onset 25 to 30 years Dark adaptation – light threshold of the peripheral retina is increased Tubular vision- loss of peripheral retina Loss of central vision P hotopsia

5. Fundus ; Signs Retinal pigmentary changes

6. Field defects

7. O ther causes for retinal pigmentary disorders syphilis, rubella , and diffuse unilateral subacute neuroretinitis  RP can be associated with deafness, obesity, kidney disease and various other general health problems, including central nervous, and genital lesions. Drugs . Thioridazine and other antipsychotics (neuroleptics, dopaminergic antagonists)

8. Investigations ; ERG . EOG

9. EOG

10. Ocular associations Myopia POAG Microphthalmos Keratoconus PSCC

11. Treatment for RP

12. Optogenetics

13. Atypical Retinitis P igmentosa TYPES Retinitis pigmentosa sine pigmento Sectoral RP Pericentric RP Retinitis punctata albescens Central Retiniti pigmemtosa Central RP

14. Vitreous Humour The vitreous humor, also called vitreous fluid . The vitreous humor comprises a large portion of the eyeball vitreous humor is a transparent, colorless, gel-like substance located in the posterior chamber of the eye. It helps 1.maintain the round shape of the eye and 2.Optical media 3.shock absorbance.

15. VITREOUS

16. PERSISTENT HEPERPLASTIC PRIMARY VITREOUS

17. PVD

18. ASTEROID HYALOSIS

19. SCNCHISIS SCINTILLANS Shower of golden rain Occurs in a damaged eye

20. VITREOUS

21. PERSISTENT HEPERPLASTIC PRIMARY VITREOUS

22. Vitreous haemorrhage

23. PVD

24. ASTEROID HYALOSIS

25. SCNCHISIS SCINTILLANS Shower of golden rain Occurs in a damaged eye

26. Vitreous haemorrhage