Rituxirel 500mg injection

helenachristy 58 views 18 slides Jul 20, 2019
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About This Presentation

rituxirel 500mg is a anticancer medicine which prevents the growth and spread of cancer cells in the body.


Slide Content

Rituxirel 500mg Injection| Rituximab Uses & Side effects MILLION HEALTH PHARMACEUTICALS

DESCRIPTION Rituxirel 500mg  is an anticancer medicine which prevents the growth and spread of cancer cells in the body .   Rituxirel 500mg injection  also indicated for the treatment of Non- Hodgkin’s lymphoma or chronic lymphocytic and with combination with another anticancer drugs like methotrexate is used for rheumatoid arthritis symptoms in adult treatment Rituxirel 500mg  with steroid regimen combination is given for the treatment of some rare disorders which cause blood vessels and other tissues inflammation in the body.

INDICATION Rituxirel 500mg  and hyaluronidase human injection are given alone or combination with other drugs to treat certain types of non-Hodgkin's lymphoma and chronic lymphocytic leukemia (cancer start in WBC ). Rituxirel 500mg injection  is also used with methotrexate ( Otrexup , Rasuvo , Xatmep , others) for the treatment rheumatoid arthritis symptoms in adults that have been already treated with some type of regimen known as tumor necrosis factor (TNF) inhibitor. 

MECHANISM OF ACTION Rituxirel 500mg injection  is a type of class called as monoclonal antibody and which is a new type of "targeted" cancer treatment and an integral part of the body's immune system.  Rituxirel 500mg  works by linking to the CD20 antigen on normal and malignant B-cells. Hence the body's essential immune security is initiated to attack and kill the marked B-cells.

PRODUCT DETAILS Brand : Rituxirel   Ingredients : Rituximab  Strength : 500mg  Manufactured : Reliance Life sciences Package : 100mg in a 1vial RITUXIREL 500mg

PHARMACOKINETICS ABSORPTION Not available DISTRIBUTION volume of distribution is 3.1 L METABOLISM Rituxirel 500mg  metabolized by human antimurine antibody production. EXCRETION Not available The half-life of NHL is 22 days and for RA is 18.0 days, GPA and microscopic polyangiitis is 23 days.

DOSAGE MANAGEMENT Rituxirel 500mg injection  is recommended to administer only through intravenous infusion not by IV push or bolus . ADMINISTRTION : Take an  Rituxirel 500mg injection  amount and diluted to final concentration of 1 mg/ml up to 4 mg/ml as infusion (containing either 0.9% Nacl or 5% dextrose in water). Invert gently the bag and mix the solution. Dispose unused drug left in vial.

PRECAUTIONS Allergic condition against  Rituxirel 500mg  or any other medication informs your doctor . While using  Rituxirel 500mg injection  do not take any vaccination or immunization without taking advice from doctors . Avoid use of  Rituxirel 500mg  if you are pregnant. It will harm the baby unborn, while using Rituxirel 500mg use correct birth control to prevent pregnancy and for at least 2 weeks after your treatment ends. Rituxirel 100mg may affect the ability to have children in women. Inform your doctor if you planning to pregnant.

SIDE EFFECTS Common effects: fever and chills (flu like symptoms) Less common side effects: Weakness ; nausea; headache; cough; dyspnea; pharyngitis

DRUG INTERACTION Rituxirel 500mg injection  drug interaction has limited data is available at present. Combination with fludarabine or cyclophosphamide has no effects in pharmacokinetics in CLL patients. Combination with methotrexate had no effects in pharmacokinetics.

CONTRAINDICATIONS Hypersensitivity or murine proteins. Active severe infections in rheumatoid arthritis Uncontrolled cardiac disease.

PREGNANCY Category C: animal studies reproduction shown an adverse effect on the fetus. The drug has no enough and well controlled studies in humans, using in pregnant women benefits by warrant use of the drug.

LACTATION Rituxirel 500mg  excreted into human milk is unknown. Due to the drug belongs to large protein molecule, no information is available. Women should not breast feed during  Rituxirel 500mg  injection treatment and 12 months following last dose.

STORAGE • Store at 20°C – 30°C • Use the drug before expiry date • Protected from direct sunlight • Do not freeze or shake. • Keep away from the children’s • Discard the unused drug by asking the advice from doctor or pharmacist.

MISSED DOSE If a dose missed to take at the time then have it suddenly before next dose timing, if time reach for next dose, then skip missed dose and continue and continue the regular schedule. Do not have 2 doses at a same time.

OVERDOSAGE If the patients had high dose of  Rituxirel 500mg  then seek immediately to the emergency department or poison control help line. Please consult the doctor for further clarification.

CONTACT US EMAIL ID :  [email protected] PHONE NO : + 91-9940472902 WEBSITE URL :  https://millionpharma.com/rituxirel-500mg.php
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