Roll 17 Inflammatory Bowel Disease Pharmacy .ppt.pptx

Roll 17 Inflammatory Bowel Disease Pharmacy

1. DENGUE HEPATITIS WITH GASTROENTERITIS By: Rohit Kumbhar CLASS: TY PHARM D Roll no :17 SUPERVISED BY- DR. KHADE SIR

2. INTRODUCTION Dengue (break-bone fever) is a viral infection that spreads from mosquitoes to people. It is more common in tropical and subtropical climates. Most people who get dengue won't have symptoms. But for those that do, the most common symptoms are high fever, headache, body aches, nausea and rash. Dengue  fever is a mosquito-borne tropical disease caused by the  dengue  virus. Symptoms typically begin 3 to 14 days after infection.

3. ETIOLOGY Dengue is a viral infection caused by the dengue virus (DENV), transmitted to humans through the bite of infected mosquitoes. About half of the world's population is now at risk of dengue with an estimated 100–400 million infections occurring each year.

4. PATHOPHYSIOLOGY

5. CLINICAL FEATURES Fever Headache Muscle and joint pain Nausea/vomiting Rash Hemorrhagic manifestations

6. DIAGNOSIS Routine blood test Tests to check the clotting process Special tests to identify the Dengue or its foot marks in our blood Urine to check protein leak

7. PHARMACOLOGICAL TREATMENT Supportive measures – Mosquito screen Avoid Aspirin . Plenty of water and salt are required Children below 12 require careful watch for dangerous form No antibiotics are of proven value There is no specific treatment for dengue. The focus is on treating pain symptoms.

8. Demographic Details Name: XYZ Age: 30 years Gender: M ale Address: XYZ DOA- 30 /09/23 DOD- 04 / 10 /23

9. Patient History No Alcohol No Smoking No Tobacco No past medication history

10. Ch ief complaints                 High grade fever -3-4 days                 Loose motion – 3-4 days                  Poor oral intake                   Nausea and vomiting Provisional Diagnosis              Acute febrile illness with severe dehydration Final Diagnosis                    Dengue Hepatitis with Thrombocytopenia with severe dehydration with Gastroenteritis

11. Investigation ØDengue Viral IgM Antibodies result > Positive ØDengue NS1 Antigen > Positive ØUSG Whole Abdomen > Mild Spleenomegaly ØPeripheral Smear > WBC- Leucopenia                                    Platelet- Mild Depletion L

12. Day 1 S/B : MO C/O : High grade fever ,General weakness Bodyache, Headache, Poor appetite G/C: Moderate BP: 120/70mmHg Pulse: 118 BPM Spo2: 97 % Respiration Rate : 16 per min CNS: Conscious P/A: Soft Rx INJ. PAN – 40 mg BD (PANTOPRAZOLE ) INJ. EMSET – 4mg BD (ONDANSETRON ) INJ. MONOCEF 1gm TDS (CEFTRIAXONE ) INJ. OPTINEURON 1AMP OD (Vit B1+Vit B6) IV FLUID NS/ RL 100ml/h TAB. LIMCEE – 500 mg OD (ASCORBIC ACID ) TAB. FOLIC ACID 5mg OD

13. Day 2 S/B : MO C/O : Bodyache, Headache General weakness Fever on and off dehydration G/C: Moderate BP: 120/80mmHg Spo2: 98 % Pulse: 92 BPM Respiration Rate : 15 per min CNS: Conscious P/A: Soft Rx INJ. PAN – 40 mg BD (PANTOPRAZOLE ) INJ. EMSET – 4mg BD (ONDANSETRON ) INJ. MONOCEF 1gm TDS (CEFTRIAXONE ) INJ. OPTINEURON 1AMP OD (Vit B1+Vit B6) IV FLUID NS/ RL 100ml/h TAB. LIMCEE – 500 mg OD (ASCORBIC ACID ) TAB. FOLIC ACID 5mg OD

14. Day 3 S/B : MO C/O : Fever on and off cough + , Loose motion + General weakness , Bodyache Headache , Dehydration G/C: Moderate BP: 180/60mmHg Spo2: 97 % Pulse: 76 BPM Respiration Rate : 16 per min CNS: Conscious P/A: Soft Rx INJ. PAN – 40 mg BD (PANTOPRAZOLE ) INJ. EMSET – 4mg BD (ONDANSETRON ) INJ. MONOCEF 1gm TDS (CEFTRIAXONE ) INJ. OPTINEURON 1AMP OD (Vit B1+Vit B6) IV FLUID NS/ RL 100ml/h TAB. LIMCEE – 500 mg OD (ASCORBIC ACID ) TAB. FOLIC ACID 5mg OD

15. Day 4 S/B : MO C/O : Loose motion decrease ,Cough Bodyache , General weakness, abdominal pain+, Mild dehydration G/C: Moderate BP: 120/80mmHg Spo2: 98 % Pulse: 92 BPM Respiration Rate : 15 per min CNS: Conscious P/A: Soft Rx TAB. DOLO 650 mg TDS ( PARACETAMOL ) TAB. MYORIL 4 mg BD ( THIOCOLCHICOSIDE ) Same Previous days drugs

16. Day 5 S/B : MO C/O : Loose motion +, severe nausea + 1 episode of vomiting, general weakness, dehydration G/C: Moderate BP: 120/ 80mmHg Spo2: 99 % Pulse: 78 BPM Respiration Rate : 15 per min CNS: Conscious P/A: Soft Rx INJ. PERINORM 10 mg SOS ( METOCHLOPRAMIDE 5mg/ml) SYP. MUCAINE 10 ml 1-1-1 (OXETACAINE + ALUMINUM HYDROXIDE +MAGNESIUM (10 mg/5 ml) Same Previous days drugs

17. Day 6 S/B : MO C/O : Bodyache, General weakness, vomiting decrease, loose motion G/C: Fair BP: 110/70mmHg Spo2 : 99 % Pulse: 80 BPM Respiration Rate : 19 per min CNS: Conscious P/A: Soft Rx Same Previous days drugs Patient got discharged

18. DISCHARGE MEDICATION Rx TAB. LIMCEE 500 mg 1-0-0 (5 days) TAB. PAN 40 mg 1-0-0 ( 5 days) TAB. REMYLIN- D 1-0-0 ( Methylcobalamin + Alpha Lipoic Acid+Vitamin B6 (Pyridoxine)+Folic Acid+Vitamin D3 (1500mcg)) TAB. UDILIV 300 mg 1-0-1 ( 7 days) (ursodeoxycholic acid ) TAB. DOMSTAL 10 mg 1-1-1 ( DOMPERIDONE ) TAB. DOLO 650 mg SOS SYP. TUSQ 10 ml 1-0-1

19. THERAPEUTIC INTERVENTION metoclopramide + acetaminophen metoclopramide increases levels of acetaminophen by enhancing GI absorption. Applies only to oral form of both agents. Minor/Significance Unknown

20. Patient Counselling

21. Reference Pharm D APP academicworks.cuny.edu https://academicworks.cuny.edu https://byjus.com/biology/dengue/