Salivary secretion

Salivary secretionn from GASTROINTESTINAL PHYSIOLOGY

1. SALIVARY GLANDS AND THEIR SECRETION

2. PAROTID GLAND

3. SUB MANDIBULAR GLAND Inferior to the body of the Mandible Produce most of the saliva (60-70 %) Ducts open through a Papilla in the floor of the mouth lateral to the Lingual Frenulum

4. SUBLINGUAL GLAND Inferior to the tongue Internal to the Oral cavity Mucosa each gland has multiple tiny sublingual ducts Open on to the Inferior surface of the oral cavity Posterior to the Submandibular duct papilla contribute on 3-5% of total saliva

5. TYPES OF CELLS IN SALIVARY GLANDS

6. COMPOSITION

7. FLOW RATE OF SALIVA

8. FUNCTIONS

9. MECHANISM OF FORMATION OF SALIVA Primary secretion Modification of saliva

10. MECHANISM OF FORMATION OF SALIVA PRIMARY SECETION FORMED BY TRANSUDATION (Pressure filtration) ISOTONIC TO PLASMA MODIFIED AS SOON AS THEY SECRETED IMP: EFFECT OF ALDOSTERONE ON DUCT CELLS

11. SYMPATHETIC STIMULATION Sympathetic nerves (NE: Nor Epinephrine)

12. REFLEX REGULATION OF SALIVARY SECRETION

13. PHYSIOLOGICAL CONDITIONS

14. CEPHALIC PHASE SECRETION OF SALIVA BEFORE ENTRY OF FOOD CONDITIONAL REFLEX BUCCAL PHASE PRESENCE OF FOOD IN THE MOUTH [(+) BUCCAL RECEPTORS] UNCONDITIONAL REFLEX& PARTIALLY REGULATED BY APETITE CENTRE OESOPHAGEAL PHASE PASSING OF FOOD THROUGH OESOPHAGUS STIMULATION OF SALIVARY GLANDS GASTRIC PHASE PRESENCE OF FOOD IN STOMACH IRRITANT FOODS IN STOMACH (VOMITING) INTESTINAL PHASE FOOD IN INTESTINE IRRITANT FOOD IN UPPER INTESTINE PHASES OF SALIVARY SECRETION

15. PHASES OF SALIVARY SECRETION Cephalic Phase

16. GASTRIC PHASE An Unconditioned reflex. Partially regulated by Appetite Centre.

17. ESOPHAGEAL PHASE GASTRIC AND INTESTINAL PHASES

18. APPLIED PHYSIOLOGY Salivary Duct Calculus: Blockage of Ducts Xerostomia : Dryness of mouth due to decreased ↓ salivary Secretion. Eg : Radiation Therapy. Sialoliths : Crystalized Saliva deposits Sialadenitis : Bacterial infections Viral Infections: Mumps Sialorrhoea : ↑ Salivary secretion