Salivation- GIT physiology

saliva- Functions. Composition, regulation of secretions, salivary glands, mechanism, applied aspects.
Parasympathetic supply to parotid, submandibular and sublingual glands.
otic ganglion and submandibular ganglion.
Mumps, xerostomia, frey syndrome, hyposecretion and hypersecretion of saliva, Sjogren's syndrome.

1. SALIVA
GIT PHYSIOLOGY

2. S.NOTOPICS COVERED
1PROPERTIES OF SALIVA
2COMPOSITION
3SALIVARY GLANDS AND SECRETIONS
4Functions of saliva
5REGULATION AND MECHANISM OF
SALIVARY SECRETION
6APPLIED ASPECTS

3. Saliva
properties
Secreted in oral cavity
It is digestive and protective
Hypotonic to plasma
Slightly acidic enzymes
1.5L per day
Specific gravity=1.002-1.012

4. COMPOSITION
Digestive
enzymes Ptyalin Lysozymes
KallikreinLipaseMucin
IgA
Cations and
anions
(electrolytes)
Organic
contents
pH= 7-8

6. SALIVARY
GLANDS AND
THEIR
SECRETIONS
–PRINCIPAL GLANDS
–Parotid gland(20%)
–Submandibular gland(70%)
–Sublingual gland(10%)
–Secretions
–Serous(ptyalin)
–Mucus(mucin, lubricating
susbtances)

7. MINOR
SALIVARY
GLANDS
LINGUAL MUCOUS GLANDS
LINGUAL SEROUS GLANDS
BUCCAL GLANDS
LABIAL GLANDS
PALATAL GLANDS
EBNER’S GLANDS (LINGUAL LIPASE)

8. FUNCTIONS
OF SALIVA

10. FUNCTIONS WITH
COMPOSISTION

11. REGULATION
OF SALIVARY
SECRETION
AUTONOMIC
PARASYMPATHETIC SYMPATHTEIC
INCREASE
SECRETION OF
SALIVA
Thin watery salivaNo antagonism

12. PARASYMPATHETIC
REGULATION
TO PAROTID GLAND
TO SUBMANDIBULAR &
SUBLINGUAL GLANDS

15. SYMPATHETIC
REGULATION

18. MECHANISM

20. APPLIED
ASPECTS

21. HYPOSALIVATION
TEMPORARYHYPOSALIVATION
Emotional conditions
Fever
Dehydration
PERMANENT HYPOSALIVATION
Sialolithiasis
Hypoplasia of salivary glands
Bell’s palsy

22. BELL’S
PALSY

23. HYPER-
SECRETION
Decay of tooth/ neoplasm
Disease of oesophagus, stomach and intestine
Cerebral palsy, mental retardation
Parkinsonism
Nausea and vomiting
Cerebral stroke

24. OTHER DISORDERS
–Xerostomia
–Drooling
–Chorda tympani syndrome
–Paralytic secretion of saliva
–Augmented secretion of saliva
–Mumps
–Sjogren’s syndrome

25. XEROSTOMIA
–DRY MOUTH/ PASTIES/ COTTONMOUTH
–Causes
–Dehydration or renal failure
–Sjogren’s syndrome
–Radiotherapy
–Trauma to salivary glands
–Adverse effects of drugs
–Marijuana

26. DROOLING
Excess production of
saliva
qOccurs in=
difficulty in swallowing
qtonsillitis
qperitonsillar abscess

27. CHORDA
TYMPANI
SYNDROME
Sweating while eating
Parasympathetic nerve fibresto
salivary glands are damaged
and during regeneration some
fibresmay deviated and join
nerve fibressupplying the sweat
glands.
When food is placed in mouth,
salivary secretion is associated
with sweat secretion.

28. MUMPS
Acute viral
infection

29. SJOGREN’S
SYNDROME
Autoimmune disorder
Exocrine glands are
destroyed
Dryness of skin, nose,
vagina, eyes and
mouth.
In sever conditions it
affects kidneys, liver,
lungs, pancreas etc.