Semisolid dosage form (paste, jellies, and poulties)

For diploma in pharmacy and B.pharmacy, M.Pharmacy

2. PASTE

3. PASTE
Content
1.Definition of paste.
2.Bases used in formulation of paste.
3.Method of preparation of paste.
4.Different between paste and ointment.
5.Storage, containers and labeling of
paste.

4. Definition of paste-
Paste can be defined as paste is a semisolid
dosage form intended for external application to
the skin. The paste are generally very thick and
stiff. They do melt at ordinary temperature and
thus from a protective coating over the area
where they are applied. They are used mainly as
antiseptic protective or soothing dressing which are
often spread on lint before being applied.

5. Bases used for preparation of paste.
1.Hydrocarbon bases. E.g. soft paraffin
and yellow paraffin.
2.Water miscible bases. E.g. Glycerin
3.Water soluble bases. E.g. PEG

6. Method of preparation of pastes-
paste are prepared by trituration and
fusion and trituration method just like
ointments. The trituration method is used
only in those cases where the base is liquid
or semisolid or solid in nature. These two
are methods has already discus in
ointments.

7. Different between paste and ointment.
PASTE OINTMENT
1.In paste containlarge
amount of solid.
2.The paste is thick and
stiff.
3.The paste les greasy.
4.Applied with spatula.
5.Protective layer.
6.Porous powder
1.In ointment medicament is
suspended/dissolved.
2.The ointment is a soft and
semisolid in nature.
3.The ointment is more greasy.
4.The ointment preparation are
applied in skin (Topical).
5.The ointment is protective or
emollient.
6.The ointment is protective for
lesions.

8. Storage, containers and labeling of paste.
the paste should be stored in well closed
container and in a cool place so as to
prevent evaporation of moisture present in
the paste.
Paste should be stored and supplied in
container made of materials which do not
allow absorption or diffusion of the contents.
“FOR EXTERNAL USE ONLY”

9. JELLIES

10. DEFINATION OF JELLIES-
Jellies can be defend as jellies are
semisolid dosage form meant for external
application to the skin or mucous
membrane. transparent or translucent non-
greasy, They may be prepared form
natural gums, such as tragacanth, pectin

11. Types of jellies-
1.Medicated jellies.
2.Lubricating jellies.
3.Miscellaneous jellies.
A. Patch testing.
B. Electro-cardiac graph.

12. Formulation of jellies-
1.Gelling agent. E.g. Tragacanth, sodium
alginate, pectin, starch, gelatin and
cellulose derivatives.
2.Preparation of jellies.
3.Preservation of jellies. E.g.
Benzoalkoniumchloride, chorocresol)
4.Storage of jellies.

13. Poultices

14. Poultices
Definition of poultices-
Poultices can be defined as poultices is a
semisolid dosage form intended to applied
to externally its soft, viscous wet masses of
solid substance to the skin for their
fomentation action in order to provide
relief from pain or reduce inflammation or
to act as counter-irritant is called as
poultices.

15. Preparation-
1.Heavy kaolin.
2.Boric acid.
3.Thymol.
4.Peppermint oil.
5.Methyl salicylate.
6.Glyverin.

16. 1.R. M. Mehta, Pharmaceutics-II, Vallabh
prakashan, 4
th
edition, page no.183-192.
2.https://www.youtube.com/watch?v=7z
kOjyFA92g.