1. (101-120 ) A 40 year old wildlife photographer for a national magazine presents to the OPD with sudden onset of fever, headache, redness of eye and myalgia. He gave a history of having a recent photography session in Bandipur National Park . On examination you observe the following : BP – 140/70 mmHg Temp - 101°F
What is the disease and identify the causative agent. Enumerate viruses causing VHF. Comment on it epidemiology in India, past and present. Explain the ecology of the causative organism and comment on the pathogenesis. Laboratory diagnosis of the disease.
2. (121-140) A 44 year old woman, working in an international NGO, presented to the OPD with fever, severe joint pains and headache. She has a history of travel to an African nation recently, where people were suffering from similar illness. The locals there used the word “ kungunyala ” to describe the condition of the illness. On further history, fever was acute, and present since 4 days. The following rash over the nose was observed, which appeared 2-3 days after onset of fever:
What is the disease, and the causative organism. Discuss the disease under the following headings: Host, Vector, mode of transmission Comment on its epidemiology in India Explain the clinical features. Laboratory diagnosis. Discuss NVBDCP related to this disease.
3. (141-160) Sunita, a 29-year-old female from Delhi came to casualty with complaints of high-grade fever, severe joint pain, back pain and myalgia . Gradually, she developed petechial rashes over the body. On examination, she was found to have jaundice, hepatomegaly and a low platelet count (30,000/ ). A tourniquet test done over the cubital fossa demonstrated 25 petechial spots/square inch area. On inquiry, she told that she has been bitten by the mosquitoes .
What is the clinical diagnosis and the etiological agent. Discuss the disease under the following headings: Host, Vector, mode of transmission. c. What are the typical clinical presentation and pathogenesis of this condition? d. How will you confirm the diagnosis? e. Treatment modality of the disease.
4. (161-180) A 21-year-old nursing student from Sierra Leone with a 3-day history of fever, malaise, headache, and general lethargy presented to the medicine department. He had worked with EVD-positive patients but reported no known PPE breaches ; however, he had shared a room with two colleagues prior to their diagnoses of EVD. He did not report vomiting, diarrhea, or hemorrhage. His vital signs were normal with an unremarkable physical examination. Hematology, biochemistry, clotting, renal, and liver function tests were all within normal parameters.
What is the diagnosis and it’s etiological agent What is the mode of transmission, host and vector of the organism What are the clinical features of the disease and it’s pathogenesis Laboratory diagnosis of the disease
5. (181-201) Rodent borne infections a. Give examples of rodent borne viral infections. What are the mode of transmission, host and vector of these organisms. b. What are the clinical features of these diseases and their pathogenesis. c. Laboratory diagnosis of the diseases.