TJ Medical Society 2008
A Presentation brought to you by:
Alison Jarmas, Jerry Liu, Nikhil Prakash, Jimmy Wu, Judy Zeng, and
the Officer Corps.
Blood Circulation and AtriaBlood Circulation and Atria
Blood enters heart through
veins: Superior vena cava and
Inferior vena cava.
Heart muscles in atria contract-
push blood into ventricles
Ventricles force blood through
the arteries.
Blood, oxygenated by lungs,
flows into left chambers of the
heart
Aorta pushes blood from heart
to the body
Blood FlowBlood Flow
Deoxygenated Blood Deoxygenated Blood
Oxygenated Blood Oxygenated Blood
Blood from tissues throughout body Blood from tissues throughout body
Superior and Inferior vena cava Superior and Inferior vena cava
Right Atrium Right Atrium
Tricuspid Valve Tricuspid Valve
Right Ventricle Right Ventricle
Pulmonary Semilunar Valve Pulmonary Semilunar Valve
Pulmonary Artery Pulmonary Artery
LungsLungs
Hearts have right
and left atria
Atria relax to fill
with blood
Atria contract to
release blood to
body
Chambers of heart
with thin walls
Diastole and SystoleDiastole and Systole
Consists of cyclic periods of high or low blood
pressure, measured in mmHg
Systole – all four heart chambers simultaneously
contract to propel blood through the cardiovascular
system; causes increased pressure on arterial walls
Diastole – the period of relaxation during which blood
flows back into the atria and ventricles; causes
decreased pressure on arterial walls
Represented as systole/diastole (ie. 120/80)
RED – aortic pressure
BLUE – left ventricular pressure
YELLOW – left atrial pressure
Ventricles and the “Cardiums”Ventricles and the “Cardiums”
Ventricles
Myocardium –
muscle tissue
Endocardium – tissue
that lines the interior
of heart
Pericardium – sac
that contains heart
and roots of great
blood vessels
Allows blood to enter ventricles
Prevents backflow into atriums
Connected to papillary muscles by chordae
tendinae
Tricuspid (right AV)
◦3 membrane flaps between right atrium and
ventricle
Bicuspid (mitral or left AV)
◦2 membrane flaps between left atrium and
ventricle
Prevents backflow from arteries to ventricles
3 small membranous pockets; crescent-
shaped flaps of endocardium
Pulmonary (right)
◦Connects pulmonary trunk to right ventricle
Aortic (left)
◦Connects aorta to left ventricle
Flaps of muscles connected to various valves
on one end by chordae tendinae and to
ventricular walls on the other
Stabilize valves
“heartstrings”
Connective tissues connecting valves to
papillary muscles
Prevent valves from being turned inside out
www.byedr.com/medicine/1781-medicine-5.html
AortaAorta
The largest artery in the body: stems from LV
and brings oxygenated blood to all parts of body
in systemic circulation.
Diagram of Aorta in SHEEP
Pulmonary CirculationPulmonary Circulation
Serves to oxygenate the depleted blood
Circuit led in to by the pulmonary trunk (artery)
Systemic circulation vena cava right atrium
right ventricle pulmonary artery (right and
left) lungs (capillary beds) pulmonary veins
(right and left) left atrium left ventricle
aorta systemic circulation
Arterioles intertwined with tubular bronchioles
bring deoxygenated blood away from the heart
Capillary beds in the saclike alveoli have
increased surface area for gas exchange by
diffusion (facilitated by a partial pressure
gradient)
Venules carry newly
oxygenated blood
back to the heart
A blood vessel that ALWAYS carries blood
toward the heart
Generally contains deoxygenated blood,
except for the pulmonary and umbilical veins
Path: Right Atrium Right Ventricle
Pulmonary Arteries Lungs Becomes
oxygenated
Very low blood pressure- rely on skeletal-
muscle pump
Smallest veins are the venules
Three Layers
◦Tunica Adventitia: Outer
covering of vessel;
composed of connective
tissue, collagen, and
elastic fiber
◦Tunica Media: Middle
layer; composed of
smooth muscle and elastic
fiber
◦Tunica Intima: Inner layer;
composed of an elastic
membrane lining and
smooth endothelium
Types:
Portal and
Nonportal
Superficial and Deep
Pulmonary and
Systemic
Major Ones:
Great Saphenous
vein (GSV) – located
in lower limbs
Pulmonary veins:
carry oxygenated air
to the lungs
Jugular Vein
Inferior and
Superior Vena Cava
Cranial/Caudal Vena CavaCranial/Caudal Vena Cava
Cranial/Caudal Vena Cava
ArteriesArteries
Arteries are a type of blood vessel
in the circulatory system. They
generally carry blood away from
the heart to the rest of the body.
The further away from the heart,
the smaller the arteries get until
they become arterioles
Arteries are tough on the outside,
muscular in the middle to help force blood
throughout, and smooth on the inside.
Generally arteries are thicker than veins
because they need to withstand greater
pressure
http://www.deconstructdesign.com/st_projects/mm_mania_2003/the_heart/functions.htm
Capillaries are the connectors between
arterioles and venules.
◦Smallest blood vessels that are involved in
regulation of osmotic pressure (internal body
heat)
◦Capillary wall consists of only the endothelium.
Venules are small blood vessels that allow
deoxygenated blood to flow from capillary
beds to veins.
◦Has endothelial membrane, muscle/elastic tissue,
and fibrous connective tissue.
Arterioles are the
blood vessels from
the arteries to the
capillaries.
Blood pressure in
arteries = result o
work needed to
pump cardiac
output through
the vascular
resistance.