Sideroblastic anaemia short PPT for students.pptx.

Sideroblastic anemia is a rare blood disorder that affects the way your body produces red blood cells. It is characterized by the presence of too much iron in the body and not enough healthy red blood cells. This can lead to symptoms such as fatigue, weakness, and pale skin.

1. Toufeeq Mallick Sideroblastic Anemia

2. Content Definition Types Symptoms Laboratory Findings Treatment Living with Sideroblastic Anemia Conclution

3. Definition Sideroblastic anemia comprise a group of disorders of diverse etiology in which the nucleated erythroid precursors in the bone marrow, show charac teristic ‘ringed sideroblasts .’

4. Types of Sideroblastic Anaemia Inherited: X-linked (most common) Autosomal dominant Autosomal recessive Acquired : Myelodysplastic syndromes (MDS) Certain medications ( isoniazid ,  chloramphenicol ) Alcohol abuse Lead poisoning Copper deficiency Chronic infections or inflammation

5. Symptoms Fatigue Weakness Pale skin Shortness of breath Dizziness Headache Enlarged spleen ( Splenomegaly )

6. LABORATORY FINDINGS The blood picture shows hypochromic anaemia which may be microcytic . Absolute values (MCV, MCH and MCHC) are reduced in hereditary type but MCV is often raised in acquired type. Bone marrow examination shows erythroid hyperplasia with usually macronormoblastic erythropoiesis . Serum ferritin levels are raised. Serum iron is usually raised with almost complete saturation of TIBC.

7. Treatment The treatment of secondary sideroblastic anaemia is primarily focussed on removal of the offending agent. No definite treatment is available for hereditary and idiopathic types of sideroblastic anemias . Some options are:- Stem cell transplantation Blood transfusition Iron cheletion therapy( Remove excess iron)

8. Living with Sideroblastic Anemia There is no cure for sideroblastic anemia , but it can be managed with treatment. People with sideroblastic anemia should: See their doctor regularly for monitoring Get enough rest Eat a healthy diet Avoid triggers ( alcohol)

9. Conclusion Sideroblastic anemia is a rare blood disorder that can affect anyone. Early diagnosis and treatment are important for managing the condition and improving quality of life. There is ongoing research to find new treatments for sideroblastic anemia .