Simple Syrup Pharmaceutics I practical WPS Office.pptx

Simple Syrup

1. T o p r e p a r e a n d s u b m i t s i m p l e s y r u p I . P . E x p e r i m e n t N o . 1 P r e s e n t e d b y M i s s S u d i p t a R o y

2. Theory of Syrup : Syrups are highly concentrated viscous aqueous solution in sugar in purified water. Syrups may be medicated or non medicated. Simple syrup consists of 66.7 % w/w of sucrose as per Indian Pharmacopoeia. If syrup contains same therapeutic agents it is called as medicated syrup. If it do not contain therapeutic agents and only contains flavouring agents and used as vehichles is called flavored syrup. eg. cherry syrup , orange syrup , coca syrup. Syrups are good demulcent and soothing agents, hence they are of special value in cough syrups of sucrose in sugar based syrup is very important. Advantage of Syrup . As sweetening agent , syrup can mask unpleasant taste of medicine. Syrups are concentrated, when it is taken by oral route, there is a feeling of soothing effects due to high viscosity in mouth and on irritated tissue of throat. Due to its taste and fluidity, syrup is given to small children and old aged patient that they can swallow this.

3. W h a t i s s i m p l e s y r u p ? Syrups are highly concentrated viscous aqueous solution in sugar in purified water. Syrups may be medicated or non medicated. Simple syrup consists of 66.7 % w/w of sucrose as per Indian Pharmacopoeia.

4. R e q u i r e m e n t s o f m a k i n g s y r u p . A p p a r a t u s . G l a s s b e a k e r ( 2 5 m l ) , S u c r o s e , M e a s u r i n g C y l i n d e r , S u c r o s e , M e a s u r i n g C y l i n d e r , P u r i f i e d W a t e r .

5. P r o c e d u r e o f m a k i n g s i m p l e s y r u p . 01) A 100 ml empty beaker was weighed and the weight was noted. 02) Half the quantity of purified water was placed in to beaker. 03 ) Calculated quantity of sucrose was weighed and added to the water. 04 ) Sucrose was dissolved by heating with occasional stirring. 05 ) After cooling , purified water was added to make up the required weight. Dose : 15 to 20 ml. Category : Pharmaceutical Aid . (Non-Medicated syrups ) Storage : Store in airtight container in cool temperature not exceeding 25 degree centrigrade. (constant temperature can be prevent Crystallization of sugar in syrup )

6. F o r m u l a t i o n T a b l e . Ingredients. Quantity Given Quantity Taken (Factor * Quantity Given)0 Sucrose 667 gm 0.02*667=13.4 gm Purified Water I.P. (q.s.) 1000 m 0.02*1000 ml = 20 ml Factor = Required quantity/Quantity given = 20 ml /1000 ml = 0.02

7. O b s e r v a t i o n T a b l e . Name of the Preparation. Test Specification Observation Smple Syrup I.P. Description Color Volume Odour Clear Colorless to slightly yellow 100 ml Odourless

8. L a b e l l i n g . Simple Syrup I.P. (20 ml ) Ingredients : Sucrose - 13.4 gm Purified water - 20 ml Category :Pharmaceutical Aid. (Non-Medicated Syrups ) Direction : As per need. Storage : Store in airtight container in cool temperature not exceeding 25 degree centrigrade. Manufacturing Date - Expiry Date - Manufactured by- Manufacturing Place - Depatment of Pharmaceutics , East POint College of Pharmacy, Janaprabha, Bidarahalli.