sneha kalpana

preparation with oil and ghee as base

1. WELCOMES U ALL SDMCAH HASSAN Dr.KISHORE 1

2. CRITICAL ANALYSIS OF SNEHA KALPANA GUIDED BY Dr.GAZALA HUSSAIN ASSO.PROF PRESENTER: Dr.D.SEETARAMA KISHORE PRELIMINARY PG SCHOLAR SDMCA&H RS&BK

3. GIST OF TOPIC Dr.KISHORE 3

4. INTRODUCTION Derivation – स्निह् प्रीतौ Sneha Fat or Fatty material Kalpana Pharmaceutical process of medicaments Eg : Ghrita kalpana and Taila kalpana Produces snigdhata to the body Dr.KISHORE 4

5. DERIVATIONS OF DRAVYAS IN SNEHA KALPANA कल्क रसपिष्ट द्रव्य पिण्डे द्रव द्रव्यम् तरलद्रव्ये स्नेह दुग्धसारि Dr.KISHORE 5 Ref --VAIDHYAKA SHABDHA SINDHU

6. DEFINITION Ghritas are preparations in which ghee is boiled with prescribed Kashayas (decoctions) and kalkas of drugs according to the formula. This process ensures absorption of the active therapeutic principles of the ingredients used Tailas are preparations in which taila is boiled with prescribed Kashayas (decoction) and kalkas of drugs according to the formula. This process ensures absorption of the active therapeutic properties of the ingredients used. Dr.KISHORE 6 Ref --AFI

7. Majja Vasa Taila Ghrita Sthavara Jangama TYPES Dr.KISHORE 7 REF —CHA.SU/13/13

8. BAHYA ABHYANTARA Dr.KISHORE 8

9. AIMS OF SNEHA KALPANA The rationality behind taking an Taila / Ghrita as a base is presumably – To Extract water soluble, lipid soluble active fractions from the ingredients used To Enhance Shelf life To Enhance the Drug Absorption Dr.KISHORE 9

10. UPAKARANA PAATRA DARVI VASTRA AGNI 10 Dr.KISHORE 10

11. IMPORTANCE OF AGNI TEEVRA AGNI MANDA AGNI Dr.KISHORE 11 STANDARDIZATION OF KSHEERABALA TAILA V. NAGESWAR RAO, T. SHANKAR, S.K DIXIT and A.B RAY Department of Rasa shastra , Institute of medical sciences , BHU Varanasi

12. ESSENTIAL INGREDIENTS Dr.KISHORE 12 R ef — Sha Ma /9/1

13. GENERAL METHOD OF PREPARATION 1:4:16 or ¼:1:4 ANUKTA MANA Dr.KISHORE 13 R ef — Sha Ma /9/1

14. PREPARATION OF KWATHA FOR SNEHA KALPANA 1/4 Dr.KISHORE 14 R ef — Sha Ma /9/2

15. BASED ON NATURE OF DRUG 4 8 16 PARTS Dr.KISHORE 15 R ef — Sha Ma /9/3

16. BASED ON QUANTITY OF DRUG 16 PARTS 8 PARTS 4 PARTS Drug Water Dr.KISHORE 16 R ef — Sha Ma /9/4

17. METHOD OF SNEHA PAKA Dr.KISHORE 17 DUGDHA REF - YR/SPVP/96 REF - B.R/5/1283-1284

18. 18 SEVEN RULES Dr.KISHORE R ef— Sha Ma /9/6-12

19. Sneha kalpana is prepared with different Drava Dravyas 1/4 th 1/6 th 1/8 th RULE NO 1 Dr.KISHORE 19 ?

20. EXAMPLES JALA KASHAYA SWARASA ARKA TAILA , ARJUNA GRITHA BALA TAILA , TRIPHALA GRITHA Dr.KISHORE 20 PINDA TAILA , JATYADI GRITHA Ref —A.F.I

21. Drava dravyas like Kalka is 1/8 th part of sneha add 4 parts of water 1/8 :1:4 DUGDHA DHADHI MAMSARASA TAKRA RULE NO 2 Dr.KISHORE 21 ?

22. EXAMPLES DUGDHA Go Dugdha Aja Dugdha Kumkumadi Taila Anu Taila DADHI Kottam Chukkadhi Taila TAKRA Grahanimihira Taila MAMSA RASA Sambukadya Taila Dr.KISHORE 22 Ref —A.F.I

23. GHRITAS with MAMSA RASA AMRITHA PRASHA GHRITA BRIHATH CHAAGALYADHI GRITHA BRIHAT ASWAGANDHA GHRITA GO DUGDA AMRITHA BHALLATAKA GHRITA KSHIRA SHATPHALA GHRITA Dr.KISHORE 23 Ref —A.F.I

24. If 4 or less they have to be four times to the quantity of sneha in total If drava dravyas are 5 or more in number then each one should be taken equal to that of sneha RULE NO 3 Dr.KISHORE 24 ?

25. EXAMPLES NILI BRINGADI TAILA DRAVA DRAVYAS are NILI SWARASA BRINGARAJA SWARASA AJA KSHIRA NARIKELA KSHIRA MAHISHI KSHIRA GO DUGDA 6 Dr.KISHORE 25 Ref —A.F.I

26. KALKA DRAVYA AND SNEHA Then DRAVA DRAVYA WATER ¼:1:4 RULE NO 4 Dr.KISHORE 26 ?

27. EXAMPLES WATER as DRAVA DRAVYA in CHITRAKADI TAILA PINDA TAILA Dr.KISHORE 27 Ref —A.F.I

28. KALKA ( Kwatha dravyas are used as Kalka dravya ) Only Sneha and KWATHA 1/6 :1:4 RULE NO 5 Dr.KISHORE 28 ?

29. EXAMPLES KETHAKI MULADI TAILA Dr.KISHORE 29 Ref —SAHASRA YOGAM

30. DRAVA DRAVYA and SNEHA WITHOUT KALKA 0:1:4 RULE NO 6 Dr.KISHORE 30 ?

31. EXAMPLES NIRGUNDI TAILA NIRGUNDI PATRA SWARASA SNEHA DRAVYA Dr.KISHORE 31

32. If Pushpa is kalka dravya Kalka is 1/8 th part of sneha 1/8:1:4 RULE NO 7 Dr.KISHORE 32 ? EXAMPLES VASA GHRITA SURASADI TAILA Ref —A.H.CHI/2/42-44 Ref —SUSRUTHA

33. SAVEERYATA AVADHI AND MATRA Dr.KISHORE 33 R ef — Sha Ma /9/1

34. SNEHA PAAKA KAALA The Duration of Paka period depends on the nature of the Drava dravyas added to Sneha . Valli , Moola - 12 days Kwatha , Aranala and Takra - 5 days Swarasa - 3 days Dugdha - 2 days Mamsa rasa, Vrihi dhanya - 1 day Dr.KISHORE 34 Ref —B.R/1/1310-1312

35. SNEHA SIDDHI LAXANAS वार्तिवत् स्नेहकल्कः स्याद् अंगुल्या विमर्दिताः शब्दहीनो अग्नि निक्षिप्तः स्नेहः सिध्दो भवेत् तदा यदा फेनोद्गमस्तैले फेनशान्तिश्च सर्पिषि गन्ध वर्ण रसोत्पत्तिः स्नेहसिध्दिः तदा भवेत् Dr.KISHORE 35 R ef — Sha Ma /9/12-13

36. ? FOAM APPEARS IN TAILA Dr.KISHORE 36

37. ? FOAM DISAPPEARS IN GHRITA Dr.KISHORE 37

38. SNEHA PAKA आम पाक निर्वीर्य अग्निमान्ध्य गुरु मॄदु पाक नस्य कर्म मध्यम पाक सर्व कर्म खर पाक अभ्य ड़गार्थं दग्ध पाक दाह् , निश्प्रयोजन Dr.KISHORE 38 R ef — Sha Ma /9/17

39. HOW TO ASSESS PAKA Ama paka Apari Paka Mridu paka Less quantity of Moisture in Kalka Madhayama paka Soft but devoid of moisture Khara paka Slightly rough to touch Dagdha paka Katina Tara Sneha kalka Dr.KISHORE 39

40. PAKA SHARANGADHARA CHARAKA SUSHRUTHA VAGBHATA MRIDU NASYA NASYA PANA NASYA MADHYAMA SARVA KARMA PANA & BASTI NASYA & ABHYANGA PANA & BASTI KHARA ABHYANGA ABHYANGA BASTI AND KARNA PURANA ABHYANGA Dr.KISHORE 40

41. ADITYA PAKA Dravya + Sneha appropriate paatra ADITYA PAKA EXAMPLE KASISADI GHRITA Kasisa Nisha Musta etc., drugs are taken in quantity of 1 Karsha and powdered 30 Pala of GHRITA kept in TAMRA PAATRA Exposed to SUN for 7 days Dr.KISHORE 41 R ef — Sha Ma /9/51-57

42. GANDHA PAKA Drugs are taken in equal quantity and powdered thoroughly and packed in cotton cloth Taila is to be taken about 16 times to that of drugs powder When Taila is boiled, the Pottali is immersed in the Taila and vessel is closed Its immersed for Ten days then the pottali is to be squeezed properly to obtain GANDHA PAKA Dr.KISHORE 42 Ref —B.R/5/1309

43. MURCHANA Sneha is subjected to one particular samskara called Sneha murchana . Applicable for both Ghrita and Taila . Durgandha vinahanthi , Ama dosha harathi Veeryavan , Soukhya dhaayi Dr.KISHORE 43 Ref —B.R/5/1285

44. GHRITA MURCHANA One Pala each One Prastha Four Prastha Pathya , Dhatri V ibhitaki J aladha R ajani Matulunga swarasa GHRITA JALA Dr.KISHORE 44 Ref —B.R/5/1285

45. TILA TAILA MURCHANA JALA MURCHITHATILATAILA 1/16 Parts 1/64 Parts 1 Part 4 Parts Dr.KISHORE 45 Ref —A.F.I

46. QUALITIES OF MURCHITHA SNEHA Significant increase in Iodine and Saponification values Decrease in the Acid value Decrease in the Rancidity Decrease in the Saturated acid profile and increase in the Unsaturation Percentage Dr.KISHORE 46 Standardization of Tila taila ( Sesamum oil ) - An Ingredient used in the Ayurvedic Vaitarana Basti Dr. Sriram Chandra Mishra, Dr. Narayan Chandra Dash . Department of Kayachikitsa , Gopabandhu Ayurveda Mahavidyalaya , Puri , Odisha

47. WHY TILA TAILA IS BEST LIGNANS Acts as anti cholesterol agents SESAMIN Protects liver from the oxidative damage Dr.KISHORE 47

48. AVARTANA Repeating the process ( sneha kalpana ) for several times means Avartana This potentiates the final product; to achieve the maximum benefit of the drug Dr.KISHORE 48 Ref —CHA.CHI.29/117-120

49. METHOD OF PREPARATION The general procedure of Sneha kalpana is followed to obtain sneha Kalka and Drava dravya are added for second Avarthy and Sneha paka is done Number of such repetitions would determine the number of AVARTANA Variation in consistency, colour and odour of the product may be observed after each Avartana Dr.KISHORE 49

50. EXAMPLES OF AVARTAYUKTA SNEHA KALPANAS KSHEERA BALA TAILA 101 DHANWANTARAM TAILA 101 Dr.KISHORE 50 PHARMACEUTICAL STUDY OF AVARTITA HINGUSAUVARCHALADI GHRITA Roshy Joseph C, Ilanchezhian R

51. KUZHAMBU Kerala Pharmacies are using Kuzhambu practically in Sneha kalpana To get more Vatahara action than the Taila by adding Eranda taila , etc. By doing this procedure viscosity of the Sneha will increase There will be no change in the ingredients but only in the Sneha dravya Dr.KISHORE 51

52. EXAMPLES Dr.KISHORE 52 Sesame oil, Cow's ghee, Castor Oil Sesame Oil, Cow ghee, Castor Oil

53. SNEHA KALPANA WITH RASA DRAVYAS Tailas like KUSHTA RAKSHASA TAILA Shuddha Parada , Shuddha Gandhaka , Sindhura , Haratala , Tamra , Manashila JATYADI TAILA ------- Tuttha VRANA RAKSHASA TAILA ….. Shuddha Parada , Gandhaka , Haratala , Manashila Tamra bhasma Dr.KISHORE 53 Ref —A.F.I

54. CONTD…. GHRITAS LIKE KASISADI GHRITA KASISA, MANASHILA, HARATALA, GANDHAKA SINDHURA, KAMPILLAKA Dr.KISHORE 54 Ref —A.F.I

55. SNEHA KALPANA IN SDM TEACHING PHARMACY Dr.KISHORE 55

56. RESEARCH WORKS PHARMACEUTICO ANALYTICAL STUDY OF SNEHA PAKA SAMAYA W.S.R. BRAHMI GRITHA AND ITS EFFECT ON MEMORY IN ALBINO RATS SARAN BABU ; SDMCA, HASSAN CHEMICAL ANALYSIS OF NIRGUNDI TAILA W.S.R.TO PREPARE IN DIFFERENT NUMBER OF DAYS PRASHANTH BK RAO K SHANKAR Dr.KISHORE 56

57. DISCUSSION Kalpana in which Agni, Jala and Kaala samskaras are used to obtain active principles is Sneha kalpana Unique procedure to extract both water and lipid soluble active principles It is administered by different routes as Bahya and A bhyantara Madhyama paka is considered as Sarva karma yukta Dr.KISHORE 57

58. CONTD….. Murchana plays an important role in Pharmaceutics and Therapeutics Avartana increases potency of the product Viscosity of Kuzhambu is more than normal Taila because of more Sneha dravyas incorporated Rules are set for complete or proper extraction of gunas (active principles) into Sneha Dr.KISHORE 58

59. CONCLUSION Sneha kalpana is widely used dosage form in Ayurvedic pharmaceutics Method of preparation and rules are explained to acquire the complete efficacy of the drugs employed More research needs to be done to revalidate the concepts explained Dr.KISHORE 59

60. Dr.KISHORE 60 VAIDHYAKA SHABDHA SINDHU AYURVEDIC FORMULARY OF INDIA SHARANGADHARA SAMHITHA ASHTANGA HRIDAYAM CHIKITSA STHANAM BHAISHAJYA RATNAVALI SAHASRA YOGAM AN EXTENSIVE CHEMICAL AND CHROMATOGRAPHICAL ANALYSIS OF AMURCHITHA, MURCHITHA AND AUSHADHA SIDDHA TAILAS PREPARED WITH AMURCHITHA AND MURCHITHA TAILAS, HIREMATH B REFERENCES

61. YOUR DREAM IS YOUR SIGNATURE Dr.KISHORE 61

62. I THANK MY TEACHERS MY FRIENDS 7 DR.KISHORE THANK YOU THANK YOU Dr.KISHORE 62

63. Dr.KISHORE 63 HAPPY CHATHURDHI GANESH IN ADVANCE